Understanding how emotions affect decision-making in adolescents who self-injure

Effects of Emotional Reactivity on Decision-Making in Adolescents With Nonsuicidal Self-Injury

Observational University of Electronic Science and Technology of China · NCT05981612

This study looks at how emotions affect decision-making in teenagers who hurt themselves and compares it to their peers who don’t, to better understand why they might make harmful choices.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages15 Years to 18 Years
SexAll
SponsorUniversity of Electronic Science and Technology of China Academic / other
Locations1 site (Chengdu, Sichuan)
Trial IDNCT05981612 on ClinicalTrials.gov

What this trial studies

This observational study investigates the role of emotional reactivity and prediction errors in dysfunctional decision-making among adolescents who engage in nonsuicidal self-injury (NSSI). The researchers aim to compare these decision-making processes in adolescents with NSSI to those in matched healthy controls. By examining how reward-related expectations and emotional responses influence social decisions, the study seeks to uncover underlying mechanisms that contribute to NSSI behaviors. Participants will be assessed based on their emotional responses to unfair experiences, providing insights into the cognitive and emotional factors at play.

Who should consider this trial

Good fit: Ideal candidates are adolescents aged 15-18 who have engaged in nonsuicidal self-injury behaviors at least five times in the past year.

Not a fit: Patients with high suicidal risk or those diagnosed with severe psychiatric disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and interventions for adolescents struggling with self-injury behaviors.

How similar studies have performed: While the specific approach of this study is novel, previous research has indicated the importance of emotional and decision-making processes in understanding NSSI behaviors.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 15-18 years
* right-handed
* normal or corrected normal visual acuity
* meet the proposed DSM-5 frequency criteria (e.g., ≥5 days of NSSI behaviors in the past year)

Exclusion Criteria:

* diagnosis of borderline personality disorder, major depressive disorder, other
* psychiatric disorders, etc.
* high suicidal risk
* recent use of medications that can affect neural activity
* have received or are receiving Dialectical Behavior Therapy (DBT) other treatment for emotional problems within the past 6 months
* have a contraindication to MRI scanning (e.g., metal implants, claustrophobia or other conditions that make them inappropriate for MRI scanning)

Where this trial is running

Chengdu, Sichuan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Nonsuicidal Self InjuryPrediction Errors
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.