Understanding how childhood stress affects heart health
Cardiovascular Health & Early Stress
This study looks at how stressful experiences in childhood can affect heart health in young people aged 9 to 30.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 9 Years to 30 Years |
| Sex | All |
| Sponsor | Virginia Commonwealth University Academic / other |
| Locations | 1 site (Richmond, Virginia) |
| Trial ID | NCT06557707 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between adverse childhood experiences (ACEs) and cardiovascular health in individuals aged 9 to 30. It aims to explore how different types of childhood stress can lead to long-term cardiometabolic issues, such as heart disease and diabetes. By examining physiological responses to stress and the cumulative effects of ACEs, the study seeks to uncover the underlying mechanisms that contribute to cardiovascular dysfunction. Participants will be assessed for their experiences with ACEs and their cardiovascular health status.
Who should consider this trial
Good fit: Ideal candidates include men and pre-menopausal women aged 18-30, as well as males and females aged 9-17 who have experienced childhood adversity.
Not a fit: Patients with existing cardiovascular, pulmonary, renal, hepatic, or cerebral diseases, as well as those with chronic pain or pregnancy, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into preventing cardiovascular diseases linked to childhood adversity.
How similar studies have performed: Other studies have shown a correlation between ACEs and health outcomes, but this specific approach to understanding cardiovascular health is less explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Cohort 1 * Men and pre-menopausal women * 18-30 years old Cohort 2 * males and females * 9-17 years old Exclusion Criteria: Cohort 1 * Evidence of cardiovascular, pulmonary, renal, hepatic or cerebral diseases * Evidence of pregnancy or currently nursing. * Having a history of chronic pain * Having a history of rheumatoid arthritis Cohort 2 * Evidence of cardiovascular, pulmonary, renal, hepatic or cerebral diseases * Evidence of pregnancy or currently nursing. * Having a history of chronic pain * Having a history of rheumatoid arthritis
Where this trial is running
Richmond, Virginia
- Virginia Commonwealth University — Richmond, Virginia, United States (Recruiting)
Study contacts
- Principal investigator: Paula Rodriguez Miguelez — Virginia Commonwealth University
- Study coordinator: Paula Rodriguez Miguelez
- Email: prodriguezmig@vcu.edu
- Phone: (804) 396-4498
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.