Understanding how autonomic function affects low blood pressure in elderly patients during surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the relationship between preoperative cardiovascular autonomic function and the occurrence of post-induction hypotension (PIH) in elderly patients undergoing general anesthesia for elective non-cardiac surgery. Researchers will measure baroreflex sensitivity (BRS) and heart rate variability (HRV) to assess autonomic function before surgery. The primary outcome will focus on the incidence of PIH, while secondary outcomes will include early intraoperative hypotension, postoperative complications, and 30-day mortality rates. The study seeks to quantify risk factors associated with PIH in this vulnerable population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 65 years old;
* Elective non-cardiac surgery;
* ASA Class I-III;
* General anesthesia;
* Use a tracheal tube as an airway management tool;
* Patients and their families can understand the research protocol and are willing to participate in this research

Exclusion Criteria:

* Severe vascular disease;
* Secondary hypertension;
* Parkinson's disease;
* Cannot measure upper extremity blood pressure for various reasons;
* Arrhythmias such as atrial fibrillation cannot perform HRV measurement;
* Mentally abnormal and unable to cooperate

Where it's running

• Peking Union Medical College Hospital
  Beijing, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.