Understanding HIV infection through blood cell studies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the virologic and immunologic parameters of HIV infection and other immune deficiency diseases using human peripheral blood cells. The research aims to elucidate the pathogenic aspects of HIV in relation to immune regulation and dysregulation. Participants will provide blood samples for analysis, which will help in understanding the disease's pathogenesis. The study is crucial due to the lack of adequate animal models for HIV research.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA:
* 18 years of age or older.
* Adequate venous access.
* Have a blood pressure less than or equal to 180/100: pulse rate 50-100, unless a lower pulse rate is considered normal for the volunteer.
* Have adequate blood counts (volunteers living with HIV: hemoglobin greater than or equal to 9.0 g/dL, platelets greater than or equal to 50,000; volunteers living without HIV: hemoglobin greater than or equal to 9.0 g/dL, platelets greater than or equal to 50,000
* Be willing and able to provide written informed consent on screening, comply with study requirements and procedures, and comply with clinic policies
* Willingness to allow blood samples to be used for future studies of HIV infection/pathogenesis, and undergo hepatitis screening

EXCLUSION CRITERIA:

* Pregnant and/or breastfeeding females.
* Active substance abuse or history of prior substance abuse that may interfere with protocol compliance or compromise volunteer safety.

Where it's running

• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting
• Washington Hospital Center
  Washington D.C., District of Columbia, United States Completed

Study contacts

• Principal investigator: Susan L Moir, Ph.D. — National Institute of Allergy and Infectious Diseases (NIAID)
• Study coordinator: Catherine A Seamon, R.N.
• Email: cseamon@cc.nih.gov
• Phone: (301) 402-3481

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.