Understanding heat regulation during exercise in military personnel

Study of Thermoregulation in Exercise Heat Stroke in the Military Environment

Observational Direction Centrale du Service de Santé des Armées · NCT05847465

This study is testing how well military personnel can handle heat during exercise to see if they are heat tolerant or not, which could help improve safety during training.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorDirection Centrale du Service de Santé des Armées Academic / other
Locations1 site (Brétigny-sur-Orge)
Trial IDNCT05847465 on ClinicalTrials.gov

What this trial studies

This observational study focuses on assessing thermoregulation in military personnel who have experienced exercise-induced heat stroke. It utilizes a Heat Tolerance Test (HTT) conducted in a controlled environment to evaluate physiological responses such as heart rate, skin temperature, and sweat loss. The study aims to differentiate between individuals who are heat intolerant and those who are heat tolerant, providing valuable insights into their thermophysiological profiles. The findings could enhance understanding of heat-related illnesses and improve safety protocols in military training.

Who should consider this trial

Good fit: Ideal candidates for this study are military personnel who have undergone exercise heat stroke and are currently trained or re-trained with a minimum of two aerobic sessions per week.

Not a fit: Patients currently on medication or those with specific contraindications, such as certain digestive issues or electronic implants, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved strategies for preventing heat stroke in military personnel during training and operations.

How similar studies have performed: While the approach of using controlled heat tolerance testing is established, this specific application in military personnel is relatively novel and has not been extensively tested in similar contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be included in the main EXPLO-CCE study;
* Subject trained or re-trained at 2 aerobic sessions per week;
* At least 2 months from the exercise heat stroke experience

Exclusion Criteria:

* Subject with a current medication treatment (for the control group only),
* Subject with a contraindication to the ingestion of a thermal capsule, namely:

  * Weight less than 37 kg
  * Inflammatory, motor or obstructive disease of the digestive tract
  * History of digestive surgery
  * Participant requiring a CT or MRI scan prior to removal of the thermal capsule (scheduled scan)
  * Presence of an implantable electronic device (e.g. pacemaker)

Where this trial is running

Brétigny-sur-Orge

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heat StrokeHeat tolerance test
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.