Understanding fluid management in critically ill patients in the ICU
Fluid Administration and Fluid Accumulation in the Intensive Care Unit (FLUID-ICU) - an International Inception Cohort Study
This study looks at how fluids are given to critically ill adults in the ICU to see how it affects their recovery and health outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Nordsjaellands Hospital Academic / other |
| Locations | 21 sites (Hillerød, Hillerød and 20 other locations) |
| Trial ID | NCT06258616 on ClinicalTrials.gov |
What this trial studies
This international cohort study aims to gather data on fluid administration practices in critically ill adult patients admitted to the intensive care unit (ICU). It will assess fluid accumulation, risk factors, and patient outcomes by collecting routinely available data over a 14-day inception period. Patients will be monitored daily until ICU discharge or death, with follow-up extending to 90 days post-admission. The study seeks to provide contemporary epidemiological insights into fluid management in the ICU setting.
Who should consider this trial
Good fit: Ideal candidates are critically ill adults aged 18 years and older who are acutely admitted to the ICU.
Not a fit: Patients with major burns or those previously included in the FLUID-ICU study may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve fluid management practices and patient outcomes in critically ill patients.
How similar studies have performed: Previous studies have highlighted the importance of fluid management in ICU settings, suggesting that this approach could yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Acute admission to the ICU during the 14-day inception period. * Adults (≥ 18 years). Exclusion Criteria: * Patients previously included in the FLUID-ICU study. * Patients with major burns (≥ 10% of body surface)
Where this trial is running
Hillerød, Hillerød and 20 other locations
- Deparment of Intensive care, Nordsjællands hospital — Hillerød, Hillerød, Denmark (Completed)
- Department of Intensive Care, Sygehus Sønderjylland Aabenraa — Aabenraa, Denmark (Not_yet_recruiting)
- Departmen of Intensive Care — Aalborg, Denmark (Active_not_recruiting)
- Department of Intensive Care, University hospital Aarhus — Aarhus, Denmark (Not_yet_recruiting)
- Department of Intensive Care, Rigshospitalet 4131 — Copenhagen, Denmark (Recruiting)
- Department of Intensive Care, Bispebjerg — Copenhagen, Denmark (Recruiting)
- Department of Intensive Care, Herlev Hospital — Herlev, Denmark (Completed)
- Department of Intensive Care, Regionshospital Gødstrup — Herning, Denmark (Active_not_recruiting)
- Department of Intensive Care, Zealand University hospital — Køge, Denmark (Completed)
- Department of Intensive Care, Regionshospitalet Randers — Randers, Denmark (Active_not_recruiting)
- Department of Intensive Care, University Hospital Zealand, Roskilde — Roskilde, Denmark (Completed)
- Department of Intensive Care, Tampere University Hospital — Tampere, Finland (Active_not_recruiting)
- Department of Intensive Care, Landspitali National University Hospital of Iceland — Reykjavik, Iceland (Completed)
- Department of Anaesthesiology, Critical Care and Pain Tata Memorial Hospital, Mumbai. — Mumbai, India (Not_yet_recruiting)
- Department of Anaesthesia and Critical Care Vilnuis University Hospital Santariskiu Cinics, Vilnuis — Vilnius, Lithuania (Active_not_recruiting)
- Department of Intensive Care Wellington Hospital (CCDHB), Newton, Wellington — Wellington, New Zealand (Completed)
- Department of Intensive Care, Stavanger University Hospital — Stavanger, Norway (Active_not_recruiting)
- Hospital Clinic of Barcelona — Barcelona, Spain (Recruiting)
- Helsingborg Hospital — Helsingborg, Sweden (Active_not_recruiting)
- Department of Intensive Care, Inselspital — Bern, Switzerland (Completed)
- General Adult Intensive Care Unit, Critical Care Directorate University Hospital of Wales, Cardiff — Cardiff, United Kingdom (Not_yet_recruiting)
Study contacts
- Study coordinator: Clara Molin, MD, PhD student
- Email: claramolinmolin@gmail.com
- Phone: +4528683965
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.