Understanding factors influencing postoperative delirium in older patients
Accompanying Scientific Program for the Quality Contract Prevention of Postoperative Delirium in the Care of Older Patients (WB-QC-POD)
This study looks at how different factors, like body clock and heart rate, might affect the chances of older patients experiencing confusion after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 70 Years and up |
| Sex | All |
| Sponsor | Charite University, Berlin, Germany Academic / other |
| Locations | 1 site (Berlin) |
| Trial ID | NCT05847010 on ClinicalTrials.gov |
What this trial studies
This observational project aims to explore the relationship between various factors and the development of postoperative delirium in older patients. It will investigate the internal circadian time, heart rate variability, and other secondary goals to gain insights into their associations with delirium rates. The study will analyze data from patients who have previously participated in the QC-POD program, focusing on perioperative conditions and physiological parameters. By examining these connections, the project seeks to enhance the understanding of delirium in the surgical context.
Who should consider this trial
Good fit: Ideal candidates are patients aged 70 years and older who are undergoing elective or non-elective surgery and have provided informed consent.
Not a fit: Patients who are moribund, have cardiac arrhythmias, or insufficient knowledge of the German language may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention strategies for postoperative delirium in older patients.
How similar studies have performed: Other studies have shown success in exploring factors related to postoperative delirium, but this specific approach is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 70 years * Male and female patients * Patients who have been included in QC-POD * Eligible patients\* for inclusion: informed consent by the patient, preoperatively with verbal and written informed consent before the start of data collection * Incapacitated patients for inclusion: Written informed consent by a legal representative * surgery (elective and not elective) Exclusion Criteria: * Moribund patients (palliative situation) * Insufficient knowledge of the German language * Cardiac arrhythmia (e.g. atrial fibrillation) * Presence of a pacemaker * Condition after heart transplantation * Inflammation in the area of the frontal sinus
Where this trial is running
Berlin
- Department of Anaesthesiology and Intensive Care Medicine, Campus Virchow-Klinikum (CVK) and Campus Charite Mitte (CCM), Charite - Universitätsmedizin Berlin — Berlin, Germany (Recruiting)
Study contacts
- Study coordinator: Claudia Spies, MD, Prof.
- Email: claudia.spies@charite.de
- Phone: +49 30 450 55 11 02
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.