Understanding factors influencing postoperative delirium in older patients
Official title: Accompanying Scientific Program for the Quality Contract Prevention of Postoperative Delirium in the Care of Older Patients (WB-QC-POD)
Run by Charite University, Berlin, Germany · NCT05847010 · Data updated 2026-11-12
This study looks at how different factors, like body clock and heart rate, might affect the chances of older patients experiencing confusion after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 70 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Charite University, Berlin, Germany Academic / other |
| Locations | 1 site (Berlin) |
| Status | Recruiting |
| Started | June 22, 2023 |
| Main results expected | July 2025 |
| Study ends | September 2025 |
| Registry record updated | January 23, 2025 |
| Trial ID | NCT05847010 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 70 years and older who are undergoing elective or non-elective surgery and have provided informed consent.
✕Probably not a fit
Patients who are moribund, have cardiac arrhythmias, or insufficient knowledge of the German language may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project aims to explore the relationship between various factors and the development of postoperative delirium in older patients. It will investigate the internal circadian time, heart rate variability, and other secondary goals to gain insights into their associations with delirium rates. The study will analyze data from patients who have previously participated in the QC-POD program, focusing on perioperative conditions and physiological parameters. By examining these connections, the project seeks to enhance the understanding of delirium in the surgical context.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention strategies for postoperative delirium in older patients.
How similar studies have gone: Other studies have shown success in exploring factors related to postoperative delirium, but this specific approach is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 70 years * Male and female patients * Patients who have been included in QC-POD * Eligible patients\* for inclusion: informed consent by the patient, preoperatively with verbal and written informed consent before the start of data collection * Incapacitated patients for inclusion: Written informed consent by a legal representative * surgery (elective and not elective) Exclusion Criteria: * Moribund patients (palliative situation) * Insufficient knowledge of the German language * Cardiac arrhythmia (e.g. atrial fibrillation) * Presence of a pacemaker * Condition after heart transplantation * Inflammation in the area of the frontal sinus
Where it's running
-
Department of Anaesthesiology and Intensive Care Medicine, Campus Virchow-Klinikum (CVK) and Campus Charite Mitte (CCM), Charite - Universitätsmedizin Berlin
Berlin, Germany Recruiting
Study contacts
- Study coordinator: Claudia Spies, MD, Prof.
- Email: claudia.spies@charite.de
- Phone: +49 30 450 55 11 02
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.