Understanding factors affecting treatment satisfaction in psoriasis patients on biological therapy

Impact of Clinical and Psychological Factors on Treatment Satisfaction in Psoriatic Patients in Biological Therapy

Observational Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT06102356

This study looks at how different medical and emotional factors affect how satisfied psoriasis patients are with their biological treatments after a year.

Quick facts

Study typeObservational
Enrollment104 (estimated)
Ages18 Years and up
SexAll
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other
Drugs / interventionsmethotrexate
Locations1 site (Roma, Lazio)
Trial IDNCT06102356 on ClinicalTrials.gov

What this trial studies

This observational study aims to identify clinical and psychological factors that correlate with treatment satisfaction among psoriasis patients receiving biological therapy for over a year. Utilizing questionnaires, the study will gather demographic, clinical, and psychological data from patients at the Dermatology Clinics of the A. Gemelli-IRCCS University Hospital. The focus is on understanding how these factors influence patient adherence to treatment and overall quality of life, despite achieving clinical response benchmarks. The findings could help tailor treatment approaches to improve patient satisfaction and outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old with a diagnosis of plaque psoriasis who have been on systemic biologics for at least one year.

Not a fit: Patients with psychiatric conditions or those with psoriasis variants such as pustular or guttate psoriasis may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance treatment satisfaction and adherence among psoriasis patients, leading to better health outcomes.

How similar studies have performed: While there is existing literature on treatment satisfaction in chronic diseases, this specific approach focusing on psoriasis and biological therapy is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with age\>18 years, of both sexes;
* Diagnosis of plaque psoriasis, with or without concomitant arthritis
* Patients who have been receiving systemic biologics for at least one year and have disease severity (PASI) and quality of life (DLQI) data available at baseline (prior to initiation of treatment);
* Signature of the written informed consent;

Exclusion Criteria:

* Presence of a psychiatric pathology already diagnosed
* Patients with psoriasis variants (pustular, guttate, palmoplantar)

Where this trial is running

Roma, Lazio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Psoriasis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.