Understanding factors affecting eye health in children

Factors Influencing Physiological Hyperopia in Children: A Prospective Nested Case-control Study

This study looks at what affects eye health in kids aged 6-9 to see how certain factors might help prevent nearsightedness from getting worse.

Quick facts

• Study type: Observational
• Enrollment: 1006 (estimated)
• Ages: 6 Years to 9 Years
• Sex: All
• Sponsor: Beijing Tongren Hospital (Academic / other)
• Locations: 1 site (Beijing, Beijing Municipality)
• Trial ID: NCT06498947 on ClinicalTrials.gov

What this trial studies

This observational study investigates the factors influencing physiological hyperopia in children aged 6-9 years, aiming to understand its role in preventing myopia progression. By establishing a prospective cohort of preschoolers, the study seeks to identify key factors that contribute to the fading of physiological hyperopia and the onset of myopia. The research is particularly focused on the critical stages of childhood development where these changes occur, providing valuable insights into eye health in young populations.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 6-9 years who can cooperate during examinations and whose parents are willing to provide informed consent.

Not a fit: Children with pre-existing conditions such as heart disease, cranial trauma, epilepsy, Down syndrome, or glaucoma may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better prevention strategies for myopia in children, potentially reducing the incidence of severe vision impairment later in life.

How similar studies have performed: While the specific focus on physiological hyperopia in this age group may be novel, previous studies have shown that understanding myopia progression can lead to effective interventions.

Eligibility criteria

Inclusion Criteria:

1. Children aged 6-9 years old, male or female;
2. Good cooperation in examination;
3. Parents cooperate and sign the informed consent form;

Exclusion Criteria:

1. Children with a history of drug allergy;
2. Pediatric patients with heart disease, cranial trauma or epilepsy, Down syndrome, or glaucoma will be excluded from the cohort.

Where this trial is running

Beijing, Beijing Municipality

• Beijing Tongren Hospital — Beijing, Beijing Municipality, China (Recruiting)

Study contacts

• Study coordinator: Huaying Xu, MD

Conditions Myopia Progression