Understanding EEG Signals During Anesthesia in Children
Study of Pharmacological and Clinical Correlates of Frontal Cortical Electroencephalographic (EEG) Signal During the Induction, Maintenance and Emergence Phases of Anesthesia in Children
Assistance Publique - Hôpitaux de Paris · NCT06020599
This study looks at how children's brains respond to anesthesia during surgery to see if monitoring brain activity can help make anesthesia safer and more effective for them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 1 Year to 18 Years |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris (other) |
| Locations | 1 site (Colombes) |
| Trial ID | NCT06020599 on ClinicalTrials.gov |
What this trial studies
This observational study collects data from children undergoing general anesthesia for surgery to analyze pharmacological and clinical correlates during the induction, maintenance, and emergence phases. It aims to assess the variability in sensitivity to anesthetic drugs and how this affects anesthesia depth, which can lead to complications. The study utilizes EEG monitoring to evaluate anesthesia adequacy, a practice that is not commonly applied in pediatric patients. By correlating EEG signals with drug administration and patient responses, the research seeks to improve anesthesia management in children.
Who should consider this trial
Good fit: Ideal candidates are children aged 1 to 18 years, weighing over 10 kg, who are scheduled for general anesthesia for surgical procedures.
Not a fit: Patients with known autism disorders or those whose parents refuse participation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the safety and effectiveness of anesthesia in children by tailoring anesthetic management to individual responses.
How similar studies have performed: While EEG monitoring in adults has shown success in anesthesia management, its application in children is less common and this approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1 year \< age \< 18 years * Weight\> 10 kg * Child receiving general anesthesia for any scheduled surgical procedure (dentistry and ENT) at Louis Mourier Hospital * Information for holders of parental authority Exclusion Criteria: * Child with known autism disorder * Refusal of parental authority holders to participate or refusal of the child * Participation in other intervention research * Not affiliated to a social security system
Where this trial is running
Colombes
- Hopital Louis Mourier — Colombes, France (RECRUITING)
Study contacts
- Principal investigator: Dan Longrois, MD, PhD — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Dan Longrois, MD, PhD
- Email: dan.longrois@aphp.fr
- Phone: 01 47 60 61 35
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Anesthesia, anesthesia