Understanding different types of Acute Lung Injury and ARDS in patients
Acute Lung/ Acute Respiratory Distress Syndrome and Extra-pulmonary Organ Injury Clinical Sub-phenotyping Study
This study is trying to understand the different types of Acute Lung Injury and ARDS in patients to help create better, personalized treatment plans.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | China-Japan Friendship Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Trial ID | NCT06123962 on ClinicalTrials.gov |
What this trial studies
This observational study aims to create a structured clinical data and biosample platform for patients with Acute Lung Injury and Acute Respiratory Distress Syndrome (ARDS) in China. By analyzing the heterogeneity among these patients, the study seeks to develop clinical, physiological, and biological sub-phenotypes that can guide personalized treatment strategies. The research will involve collecting clinical data and biological samples from various provinces, utilizing mathematical and machine learning models to establish a classification system for the condition. The classification model will be validated using international databases and cohorts to ensure its reliability and applicability.
Who should consider this trial
Good fit: Ideal candidates for this study are adults diagnosed with Acute Respiratory Distress Syndrome according to the latest global criteria.
Not a fit: Patients under 18 years old or those who decline to participate will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved individualized treatment strategies and better outcomes for patients with ARDS.
How similar studies have performed: Other studies have shown promise in sub-phenotyping ARDS, but this approach aims to create a comprehensive national database, making it a novel effort.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Meet the diagnostic criteria for Acute Respiratory Distress Syndrome (ARDS) according to the updated global definition in 2023. * The patient or their legal representative signs an informed consent form. Exclusion Criteria: * Individuals aged less than 18 years old. * Those who refuse to participate in the study.
Where this trial is running
Beijing
- Jingen Xia — Beijing, China (Recruiting)
Study contacts
- Study coordinator: Jingen Xia, M.D
- Email: 13466396561@163.com
- Phone: +8613466396561
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.