Understanding decision-making and movement in mild cognitive impairment
Online Interplay Between Deciding and Acting With Mild Cognitive Impairment
This study is testing how mild cognitive impairment affects the way people make decisions and move by looking at their brain function and movement skills.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 45 Years to 90 Years |
| Sex | All |
| Sponsor | University of Delaware Academic / other |
| Locations | 1 site (Newark, Delaware) |
| Trial ID | NCT06493422 on ClinicalTrials.gov |
What this trial studies
This study investigates how mild cognitive impairment affects the relationship between decision-making and movement. Researchers will conduct human reaching experiments to determine if this condition disrupts the interplay between cognitive and motor functions. Additionally, they will utilize Magnetic Resonance Elastography to assess brain stiffness in areas related to decision-making and motor control. The goal is to uncover mechanisms that contribute to impaired movement and decision-making in individuals with mild cognitive impairment.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 45 to 90 with a clinical diagnosis of amnestic mild cognitive impairment.
Not a fit: Patients with significant movement impairments or other neurological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to improved detection of mild cognitive impairment and more effective neurorehabilitation strategies.
How similar studies have performed: While the interplay between decision-making and motor control is a relatively novel area of investigation, similar studies have shown promising results in understanding cognitive impairments.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. age 45 - 90 years 2. Perfect or corrected vision 3. Ability to reach 4. Neurotypical Age-Matched control participants - No history of neurological disorders or injury. 5. Mild Cognitive Impairment participants - clinical diagnosis of amnestic mild cognitive impairment. Exclusion Criteria: 1. Any injury or condition that impacts reaching 2. Traumatic brain injury, such as concussion, in the last 6 months. 3. Neurotypical Age-Matched control participants: Modified Telephone Interview for Cognitive Status (TICS-m) score \< 34 4. Mild Cognitive Impairment participants: Modified Telephone Interview for Cognitive Status (TICS-m) score \> 34 5. Mild Cognitive Impairment participants: Mini-Mental State Examination Second Edition (MMSE-2) score \< 21.
Where this trial is running
Newark, Delaware
- University of Delaware — Newark, Delaware, United States (Recruiting)
Study contacts
- Principal investigator: Josh Cashaback — University of Delaware
- Study coordinator: Joshua Cashaback
- Email: joshcash@udel.edu
- Phone: (302) 831-2792
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.