Understanding cognitive and emotional profiles in Multiple Sclerosis

The MS-CEBA Study: Determining Cognitive, Energetic, Behavioural and Affective (CEBA) Profiles in Multiple Sclerosis

Observational University Medical Center Groningen · NCT06016309

This study is trying to understand how thinking and feeling differently affects the daily lives of people with Multiple Sclerosis to help improve their care.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorUniversity Medical Center Groningen Academic / other
Locations1 site (Groningen, Provincie Groningen)
Trial IDNCT06016309 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the cognitive, energetic, behavioral, and affective (CEBA) profiles in individuals diagnosed with Multiple Sclerosis (MS). It focuses on identifying non-physical symptoms that significantly impact the quality of life and societal participation of patients. By conducting neuropsychological assessments, the study seeks to highlight the prevalence and interrelation of CEBA symptoms among patients with MS, which are often overlooked in traditional treatment approaches. The findings may help in recognizing these symptoms earlier and improving treatment strategies for affected individuals.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 18-70 with a confirmed diagnosis of Multiple Sclerosis who can communicate adequately in Dutch.

Not a fit: Patients with other neurological or major psychiatric conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better recognition and treatment of non-physical symptoms in MS, enhancing patients' quality of life.

How similar studies have performed: While studies have explored cognitive and emotional aspects in MS, this specific focus on CEBA profiles is relatively novel and may provide new insights.

Eligibility criteria

Show full inclusion / exclusion criteria
In order to be eligible to participate in this study, a patient must meet all of the following criteria:

Inclusion Criteria:

* Confirmed MS diagnosis (all subtypes);
* Age18-70;
* Adequate command of the Dutch language.

Exclusion Criteria:

* Not being able to participate in a short neuropsychological assessment (NPA) as judged by the MS clinician and/or investigator;
* Presence of any other neurological and/or major psychiatric condition.

The group of HC's will be matched to the patient group on age and education level.

Where this trial is running

Groningen, Provincie Groningen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Multiple Sclerosis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.