Understanding chronic pain in hemophilia patients

Status of Chronic Pain in Patients With Hemophilia.

Observational University Hospital, Clermont-Ferrand · NCT05202951

This study is trying to understand chronic pain in people with hemophilia to see how it affects them and what treatments they use.

Quick facts

Study typeObservational
Enrollment350 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Clermont-Ferrand Academic / other
Locations10 sites (Bordeaux and 9 other locations)
Trial IDNCT05202951 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess chronic pain in patients with hemophilia, focusing on its characteristics, associated comorbidities, and the analgesic treatments used. By utilizing questionnaires administered through the RedCap web platform, the study will gather data from a minimum of 350 patients across six investigator centers over a 12-month period. The goal is to improve the management of chronic pain in hemophilia, which is often under-recognized and inadequately treated.

Who should consider this trial

Good fit: Ideal candidates include adults with hemophilia of any severity or carrier females with low levels of hemophilia.

Not a fit: Patients who do not understand French or have cognitive disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better pain management strategies for hemophilia patients, improving their quality of life.

How similar studies have performed: While there are few studies on chronic pain in hemophilia, this approach is novel in its comprehensive assessment of pain characteristics and treatment efficacy.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient with haemophilia of any severity,
* Carrier female with low levels haemophilia (\< 40%),
* ≥ 18 years of age and capable of giving informed consent to participate in research.

Exclusion Criteria:

* Patient's refusal to participate in the survey,
* Patient does not understand enough French (written and spoken) to complete the survey,
* Patient unable to complete the survey for logistical reasons (lack of internet access),
* Patient under protective measures (guardianship),
* Patients with known addictive comorbidities and/or cognitive disorders.

Where this trial is running

Bordeaux and 9 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic PainHemophilia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.