Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding Chronic Lymphocytic Leukemia

Run by Dana-Farber Cancer Institute · NCT04028531 · Data updated 2026-11-12

This study is collecting tissue samples and medical information from people with Chronic Lymphocytic Leukemia to see what causes the disease and find better treatments.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment2750 (estimated)
SponsorDana-Farber Cancer Institute
Academic / other
Locations1 site (Boston, Massachusetts)
StatusRecruiting
StartedSeptember 29, 1999
Main results expectedSeptember 29, 2030
Study endsSeptember 29, 2032
Registry record updatedOctober 13, 2026
Trial IDNCT04028531 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study include new and existing patients diagnosed with Chronic Lymphocytic Leukemia or related low-grade lymphoproliferative disorders.

Probably not a fit

Patients who do not have Chronic Lymphocytic Leukemia or related conditions may not receive any benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to collect tissue samples and medical information from patients with Chronic Lymphocytic Leukemia (CLL) to investigate the underlying causes and biology of the disease. By analyzing these samples, researchers hope to gain insights that could lead to the development of more effective therapies for CLL. The study includes both new and existing patients treated at the Dana-Farber Cancer Institute and focuses on various low-grade lymphoproliferative disorders.

Why it matters

Potential benefit: If successful, this study could lead to improved therapies for patients suffering from Chronic Lymphocytic Leukemia.

How similar studies have gone: Other studies focusing on the biology of Chronic Lymphocytic Leukemia have shown promise, suggesting that this approach could yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* New and existing patients seen for treatment of monoclonal B-cell lymphocytosis
* Any low grade lymphoproliferative disorder
* Chronic Lymphocytic Leukemia in the Dana Farber Cancer Institute Hematologic Oncology Clinic or elsewhere

Exclusion Criteria:

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Where it's running

  • Dana Farber Cancer Institute
    Boston, Massachusetts, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.