Understanding carotid web and its link to cerebral infarctions
French Cohort of Carotid Web Associated With Cerebral Infarctions
This study is trying to learn more about carotid web lesions and how they cause strokes, especially in the black community, to improve diagnosis and treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Bordeaux Academic / other |
| Locations | 1 site (Bordeaux) |
| Trial ID | NCT04431609 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze the characteristics of carotid web lesions, which are rare but often lead to severe cerebral infarctions, particularly in the black population. By establishing a multicentric cohort, the study seeks to gather comprehensive data on the prevalence and features of carotid web lesions, as well as their impact on stroke outcomes. Patients will be selected from participating Stroke Units, and their clinical and imaging data will be collected and validated by expert neurologists and neuroradiologists. The goal is to improve diagnosis and treatment strategies for this condition.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have imaging evidence of a carotid web and have experienced a cerebral infarction or transient ischemic attack.
Not a fit: Patients under 18 years old or those who oppose participation in the cohort will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better identification and management of carotid web lesions, potentially reducing the recurrence of ischemic strokes.
How similar studies have performed: While there is limited data on carotid web lesions, the establishment of a multicentric cohort for this condition is a novel approach that has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years * Available imaging revealing the presence of a carotid web * Cerebral infarction or transient ischemic attack in the carotid area downstream of a carotid web lesion. * Validation of the carotid web by a pair of experts Neurologist and Neuroradiologist * Agreement of the patient or the support person given after reading the information and non-opposition form Exclusion Criteria: * Age \<18 years * Patient expressing opposition to be enrolled in the CAROWEB cohort
Where this trial is running
Bordeaux
- CHU de Bordeaux — Bordeaux, France (Recruiting)
Study contacts
- Study coordinator: Stéphane OLINDO, M.D
- Email: stephane.olindo@chu-bordeaux.fr
- Phone: 05 57 82 12 63
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.