Understanding breast cancer-related lymphedema

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the mechanisms behind upper limb lymphedema following breast cancer surgery. It will recruit female patients who have undergone or are expected to undergo breast cancer resection and utilize various advanced imaging techniques, including Indocyanine Green lymphography and Lymphoscintigraphy, to identify lymphatic blockages. Additionally, Shear Wave Elastography will assess tissue compliance, while DXA body composition analysis will compare limb composition ratios. The study seeks to explore the relationships among lymphatic circulation, limb circumference, tissue compliance, and blood flow changes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female patients who are expected to undergo breast cancer resection surgery or have already undergone breast resection surgery for breast cancer.
* Absence of unhealed open wounds or other conditions unsuitable for tactile measurements within the measurement area.
* No severe cognitive or emotional impairments.
* No substance abuse (alcohol or drugs).
* Females aged between 20 and 80, capable of fully complying with the requirements of this study plan.

Exclusion Criteria:

* Presence of unhealed open wounds or other conditions unsuitable for tactile measurements within the measurement area.
* Upper limb abnormalities in function (including joint mobility and muscle strength).
* Significant cognitive, auditory, or expressive language issues that hinder comprehension and compliance with instructions.
* Lack of assistance for daily measurements.

Where it's running

• Kaohsiung Veterans General Hospital
  Kaohsiung City, Taiwan Recruiting

Study contacts

• Study coordinator: Zheng Yu Hoe
• Email: jhoe@vghks.gov.tw
• Phone: +886935517631

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Use of reconstructive microsurgery to treat lymphedema

  This study tests whether reconstructive microsurgery, with or without the help of indocyanine green imaging, can help people with lymphedema feel and function better by improving lymphatic drainage.

  Recruiting Istituto Ortopedico Rizzoli · Bologna · NCT07889856

• Predicting lymphedema risk in inflammatory breast cancer patients using preoperative body impedance analysis

  This study tests whether a preoperative bioimpedance test can help identify IBC patients who are at risk for developing lymphedema.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT07855627

• Boosted compression for lower limb edema

  This study tests whether applying a multicomponent short-stretch bandage three times daily (boosted compression) helps reduce edema faster in people with chronic edema or lymphedema of the legs, compared with the standard single daily bandage.

  Recruiting at 4 sites Universiteit Antwerpen · Edegem, Antwerp and 3 other locations · NCT07708662

• Erector Spinae Block vs Paravertebral Block for Chronic Pain After Mastectomy

  This trial tests whether an erector spinae block can better prevent chronic pain after mastectomy than a paravertebral block in adults 18–80.

  Recruiting American University of Beirut Medical Center · Beirut · NCT07561411

• Resistance exercise for people with lower-limb lymphedema

  This study tests whether short periods of supervised resistance exercise, with and without compression garments, change swelling or symptoms in people with lower-limb lymphedema.

  Recruiting Herlev and Gentofte Hospital · Herlev · NCT07558317

• Tracking body composition changes after breast cancer treatment

  This project will see how muscle mass and fat distribution change over two years in adults treated for stage I–III breast cancer.

  Recruiting Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · New Taipei City, Xindian Dist · NCT07472803

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.