Understanding brain responses in epilepsy patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how the brain's prefrontal and medial temporal regions respond to cognitive tasks in epilepsy patients. By utilizing the NeuroPace RNS system and monitoring local-field potentials, researchers aim to uncover the neurophysiological mechanisms behind adaptive behavior in novel situations. The focus is on patients who have intracranial electrodes placed for clinical evaluation of their epilepsy, allowing for detailed observation of neuronal activity during cognitive tasks. The findings could enhance our understanding of cognitive flexibility in epilepsy and inform future therapeutic strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Eligible subjects include both male and female patients, between 10 years of age and 64 years of age, who undergo placement of intracranial electrodes for clinical characterization of epilepsy.

Exclusion Criteria:

* Grounds for exclusion would include inability to understand and follow instructions, or inability to concentrate sufficiently to achieve a high proportion of correct responses.

Where it's running

• University of California, Los Angeles
  Los Angeles, California, United States Recruiting
• Baylor College of Medicine
  Houston, Texas, United States Recruiting
• University of Utah
  Salt Lake City, Utah, United States Active not recruiting

Study contacts

• Study coordinator: Sameer Sheth, MD, PhD
• Email: sasheth@bcm.edu
• Phone: 713-798-5060

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.