Understanding brain monitoring during general anesthesia with CONOX device
Describe Relationship Between qCON and qNOX of the CONOX Monitor During General Anesthesia Perfromed With Propofol and Remifentanil Target Controlled Infusion (TCI)
University of Padova · NCT06349681
This study is testing how well two brain monitoring tools work together during general anesthesia to help doctors manage sedation and pain for patients receiving specific medications.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 14 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | Female |
| Sponsor | University of Padova (other) |
| Locations | 1 site (Treviso, TV) |
| Trial ID | NCT06349681 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between two indices, qCON and qNOX, which are used for monitoring sedation and analgesia during general anesthesia. The study will involve patients undergoing total intravenous anesthesia with targeted controlled infusion of Propofol and Remifentanil while utilizing the CONOX neuromonitoring device. Researchers will also assess the correlation of these indices with electromyography (EMG) and the concentrations of the anesthetic agents. The goal is to clarify how these indices differentiate from each other and their relevance in anesthesia management.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for general anesthesia using targeted controlled infusion of Propofol and Remifentanil.
Not a fit: Patients with neurological or psychiatric diseases, obesity, or those receiving locoregional anesthesia may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the safety and effectiveness of anesthesia monitoring, leading to improved patient outcomes during surgery.
How similar studies have performed: While the approach of using EEG monitoring in anesthesia is established, the specific relationship between qCON and qNOX indices is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergo general anaesthesia with Targeted Controlled Infusion of Propofol (Eleveld or Schnider model) and Remifentanil (Minto model) and CONOX monitoring Exclusion Criteria: * Neurological disease * Psychiatric disease * Obesity * Locoregional anesthesia
Where this trial is running
Treviso, TV
- Treviso Regional Hospital — Treviso, TV, Italy (RECRUITING)
Study contacts
- Study coordinator: Federico Linassi, MD
- Email: federico.linassi@gmail.com
- Phone: 0422322440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Anesthesia Brain Monitoring, Anesthesia brain Monitoring, TIVA-TCI, CONOX