Understanding body perception in children with overgrowth syndromes

Body Representation, Neuropsychological Profile and Socio-emotional Development in Children With Overgrowth Syndromes, With a Specific Focus on Functional Assessment of Patients With Beckwith-Wiedemann Syndrome and Sotos Syndrome

Observational IRCCS Eugenio Medea · NCT04993235

This study is trying to understand how children with Sotos Syndrome and Beckwith-Wiedemann Syndrome see and think about their bodies to help improve support for them.

Quick facts

Study typeObservational
Enrollment92 (estimated)
Ages5 Years to 18 Years
SexAll
SponsorIRCCS Eugenio Medea Academic / other
Locations1 site (Bosisio Parini, Lombardia)
Trial IDNCT04993235 on ClinicalTrials.gov

What this trial studies

This observational study focuses on children and adolescents diagnosed with Sotos Syndrome (SS) and Beckwith-Wiedemann Syndrome (BWS), both of which are characterized by excessive growth and associated cognitive and behavioral challenges. The research aims to provide a detailed assessment of the neuropsychological and behavioral profiles of these individuals, utilizing various questionnaires and experimental tasks to gather data. By exploring the complexities of body representation and perception, the study seeks to fill existing gaps in knowledge regarding the developmental aspects of these syndromes. The findings could inform better support and interventions for affected individuals.

Who should consider this trial

Good fit: Ideal candidates for this study are children and adolescents diagnosed with Sotos Syndrome or Beckwith-Wiedemann Syndrome.

Not a fit: Patients with severe motor and sensory deficits or those with neurological or psychiatric conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and support strategies for children with overgrowth syndromes, enhancing their developmental outcomes.

How similar studies have performed: While there has been some research on neuropsychological profiles in Sotos Syndrome, this study represents a novel investigation into the behavioral functioning of children with Beckwith-Wiedemann Syndrome.

Eligibility criteria

Show full inclusion / exclusion criteria
Children and Adolescents with SS and BWS

Inclusion Criteria:

* diagnosis of Sotos Syndrome/Beckwith-Wiedemann Syndrome

Exclusion Criteria:

* severe motor and sensorial deficits that could interfere with tasks execution

Adolescents with typical development

Exclusion Criteria:

* any neurological or psychiatric conditions (e.g., learning disability, behavioral disorders etc.)

Where this trial is running

Bosisio Parini, Lombardia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sotos SyndromeBeckwith-Wiedemann SyndromeOvergrowth SyndromeBody ImageBody SchemaNeuropsychological profileBehavioral assessmentBody perception
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.