Understanding baby brain development and its relation to neurodevelopmental conditions

Brain Imaging and Infant Development

Observational King's College London · NCT04443179

This study is trying to understand how babies' brains develop from before birth to age four to see if it can help spot early signs of conditions like Autism or ADHD.

Quick facts

Study typeObservational
Enrollment790 (estimated)
Ages16 Years to 75 Years
SexAll
SponsorKing's College London Academic / other
Locations1 site (London)
Trial IDNCT04443179 on ClinicalTrials.gov

What this trial studies

The Brain Imaging in Babies study (BIBS) aims to enhance our understanding of brain development in infants from before birth to 3-4 years of age. Utilizing advanced MRI technology alongside traditional behavioral assessments, the study captures critical data on how the brain develops in diverse populations. The goal is to identify early indicators that may predict the likelihood of developing conditions such as Autism Spectrum Disorder (ASD) or Attention Deficit Hyperactivity Disorder (ADHD). This research could lead to early interventions for children at risk, improving long-term outcomes.

Who should consider this trial

Good fit: Ideal candidates include pregnant mothers and their infants, particularly those with or without a family history of neurodevelopmental conditions.

Not a fit: Patients who are not pregnant or whose infants do not meet the inclusion criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enable early identification and intervention for children at risk of neurodevelopmental conditions.

How similar studies have performed: Other studies have shown promise in using MRI to understand brain development, suggesting that this approach could yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Pregnant mothers with and without confirmed COVID-19
* Infants with and without an immediate family history of Autism Spectrum and neurodevelopmental conditions
* Based in England, UK

Exclusion Criteria:

* based on further screening

Where this trial is running

London

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Autism Spectrum DisorderAttention Deficit Hyperactivity DisorderNeurodevelopmental ConditionsCOVID-19
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.