Understanding Autoimmune Polyglandular Syndrome Type II in Taiwan
Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan
National Taiwan University Hospital · NCT05578105
This study looks at how common Autoimmune Polyglandular Syndrome Type II is in Taiwan and what it looks like in patients who have at least two related conditions like type 1 diabetes and thyroid disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 650 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital (other) |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05578105 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the prevalence, clinical characteristics, and genetic variations associated with Autoimmune Polyglandular Syndrome Type II (APS II) in Taiwan. It focuses on patients who have been diagnosed with at least two of the following conditions: type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency. By analyzing data from patients treated at National Taiwan University Hospital between 2006 and 2021, the study seeks to enhance understanding of this autoimmune disorder. No interventions will be administered, as the study is purely observational.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 20 and older who have been diagnosed with at least two of the specified autoimmune conditions.
Not a fit: Patients under the age of 20 will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could improve diagnosis and management strategies for patients with Autoimmune Polyglandular Syndrome Type II.
How similar studies have performed: While there may be studies on autoimmune syndromes, this specific focus on APS II in Taiwan is relatively novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients visited NTUH during 2006-2021, and had at least two of the three diseases: type 1 DM, primary adrenal insufficiency, and autoimmune thyroid disease. Exclusion Criteria: * Patients aged less than 20 years old
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (RECRUITING)
Study contacts
- Study coordinator: Shyang-Rong Shih, MD, PhD
- Email: srshih@ntu.edu.tw
- Phone: +886-972653337
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Autoimmune Polyendocrine Syndrome Type II