Understanding Arrhythmogenic Cardiomyopathy and its Treatment
Official title: Risk Stratification, Early Prevention and Treatment Strategies for Arrhythmogenic Cardiomyopathy (STARTER): a Multicenter Retro-prospective Cohort Study
Run by First Affiliated Hospital Xi'an Jiaotong University · NCT06352307 · Data updated 2026-11-12
This study is trying to learn more about Arrhythmogenic Cardiomyopathy by collecting health information and samples from patients to see how the condition behaves and what the long-term outcomes are.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1500 (estimated) |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Status | Recruiting |
| Started | April 9, 2024 |
| Main results expected | August 31, 2030 |
| Study ends | August 31, 2032 |
| Registry record updated | July 12, 2024 |
| Trial ID | NCT06352307 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who have been diagnosed with Arrhythmogenic Cardiomyopathy.
✕Probably not a fit
Patients with incomplete clinical data or those who do not consent to participate will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on patients diagnosed with Arrhythmogenic Cardiomyopathy (ACM) at the First Affiliated Hospital of Xi'an Jiaotong University and other centers. It aims to collect clinical data and biological samples from patients with various ACM phenotypes. By establishing a disease cohort and conducting long-term follow-ups, the study will explore the characteristics, progression, clinical features, natural course, and long-term prognosis of ACM.
Why it matters
Potential benefit: If successful, this study could lead to improved risk stratification and early treatment strategies for patients with Arrhythmogenic Cardiomyopathy.
How similar studies have gone: Other studies have explored similar approaches in understanding ACM, but this specific cohort and methodology may provide novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18 years old. * The diagnosis of ACM was confirmed by cardiac ultrasound, electrocardiogram, magnetic resonance angiography, pathological examination and gene sequencing. * Patients or their families agreed to participate in the study and authorized informed consent. Exclusion Criteria: * Incomplete clinical data. * Do not agree to the inclusion or refuse to authorize the informed consent.
Where it's running
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First Affiliated Hospital of Xi'an Jiantong University
Xi'an, Shaanxi, China Recruiting
Study contacts
- Principal investigator: Yang Yan — First Affiliated Hospital Xi'an Jiaotong University
- Study coordinator: Yang Yan
- Email: yangyan3@xjtu.edu.cn
- Phone: +86.29.85323869
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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S-ICD Eligibility Over Time in Arrhythmogenic Cardiomyopathy
This study checks whether adults with arrhythmogenic cardiomyopathy stay eligible for a subcutaneous ICD over 18 months.
-
T1 mapping to characterize heart tissue in common heart diseases
This project tests whether T1 mapping MRI scans, including dye-free native T1, can define normal and disease-specific heart tissue values for adults with various heart conditions.
-
Assessing patient characteristics and clinical course for those with PKP2-ACM
This study looks at the experiences and health changes of people with PKP2-ACM over time to better understand the condition and its impact on their lives.
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Atorvastatin 80 mg to slow progression of arrhythmogenic cardiomyopathy
This trial will try daily high-dose atorvastatin (80 mg) versus placebo in adults with arrhythmogenic cardiomyopathy to see if it prevents right ventricular functional decline and related electrical and structural worsening.
-
Identifying patients with cardiomyopathy for potential heart transplantation
This study is trying to find new ways to identify and understand cardiomyopathy in patients to better predict if they might need a heart transplant in the future.
-
Predicting Ventricular Tachycardia Events in Patients with Non-Ischemic Cardiomyopathy
This study is trying to see if certain heart imaging tests can help predict the risk of dangerous heart rhythms and sudden cardiac death in people with non-ischemic cardiomyopathy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.