Understanding Anti-IgLON5 Disease and its Outcomes
Identification, Clinical Characterization, and Prognosis of Anti-IgLON5 Disease
This study is trying to learn more about Anti-IgLON5 disease by looking at how it affects sleep, movement, and overall health in people diagnosed with it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Bron) |
| Trial ID | NCT06131346 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on characterizing the clinical features and outcomes of patients diagnosed with Anti-IgLON5 disease, a neurological disorder linked to specific antibodies. The study aims to gather and evaluate clinical and paraclinical data from participants to better understand the disease's impact on sleep, bulbar function, and gait stability. By analyzing these data, researchers hope to clarify the immune-mediated nature of the disease and its association with certain genetic markers.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who test positive for Anti-IgLON5 antibodies.
Not a fit: Patients who do not have Anti-IgLON5 antibody positivity or lack sufficient clinical data will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management strategies for patients suffering from Anti-IgLON5 disease.
How similar studies have performed: While the specific approach of this study is novel, there is growing evidence supporting the immune-mediated pathogenesis of similar autoimmune encephalitides.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients \> 18 ans * Anti-IgLON5 antibody positivity Exclusion Criteria: - Lack of clinical data
Where this trial is running
Bron
- Hospices Civils de Lyon — Bron, France (Recruiting)
Study contacts
- Study coordinator: Jerome Honnorat, professor
- Email: jerome.honnorat@chu-lyon.fr
- Phone: 33472357806
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.