Understanding and managing pediatric relapsing polychondritis in France
Pediatric Relapsing Polychondritis : Diagnosis and Management in a French Retrospective Study
This study is trying to learn more about pediatric relapsing polychondritis by looking at past cases to see how well different treatments work for children with this rare condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20 (estimated) |
| Ages | 1 Year to 17 Years |
| Sex | All |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT06019221 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather data on pediatric relapsing polychondritis, a rare condition affecting children. Given the low incidence of this disease, the study seeks to improve understanding of its diagnosis and management by analyzing historical cases from 2008 to 2022. The focus is on evaluating existing treatment approaches, including immunomodulatory therapies and biotherapies, to identify their effectiveness and potential complications. By collecting and analyzing this data, the study hopes to provide insights that can lead to better treatment strategies for affected children.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 1 to 17 years diagnosed with relapsing polychondritis between 2008 and 2022.
Not a fit: Patients with associated pathologies that could bias treatment efficacy or complications related to relapsing polychondritis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols and outcomes for children suffering from relapsing polychondritis.
How similar studies have performed: While data on pediatric relapsing polychondritis is limited, similar studies in adult populations have shown promise in understanding treatment responses.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Minor subject aged 1 to 17 years * Diagnosis of atrophic polychondritis between 01/01/2008 to 31/12/2022. * Subject (and/or his parental authority) who has not expressed, after being informed, his opposition to the reuse of his data for the purposes of this research. Exclusion criteria: * Subject (or his parents) having expressed his (their) opposition to participating in the study * Associated pathologies that cannot be related to the diagnosis of atrophic polychondritis and whose prognosis can lead to biases in the efficacy and/or complications related to treatments.
Where this trial is running
Strasbourg
- Service de Pédiatrie 1 - CHU de Strasbourg - France — Strasbourg, France (Recruiting)
Study contacts
- Study coordinator: Ariane ZALOSZYC, MD
- Email: ariane.zaloszyc@chru-strasbourg.fr
- Phone: 33 3 88 12 77 42
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.