Understanding and managing immune system disorders in patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on Inborn Errors of Immunity, a group of inherited diseases affecting the immune system. It aims to clinically and molecularly characterize both pediatric and adult patients with confirmed or suspected immune disorders. Evaluations include standard blood tests, lymphocyte typing, immunoglobulin levels, vaccination responses, and genetic investigations. Patients will be treated according to standard clinical practices while data is collected retrospectively and prospectively.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients with confirmed or suspected Inborn Errors of Immunity;
* age \< 50 years at onset of clinical features suspected for Inborn Errors of Immunity;
* obtaining informed consent from patients or parents/legal guardian of pediatric patients.

Exclusion Criteria:

• patients in whom infectious susceptibility and immunodysregulation can only be attributed to known non-immunological causes: acquired immunodeficiency secondary to chronic infections (HIV), and acquired immunodeficiency secondary to immunosuppressive treatment.

Where it's running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna
  Bologna, Bolgona, Italy Recruiting

Study contacts

• Principal investigator: Francesca Conti, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
• Study coordinator: Francesca Conti
• Email: francesca.conti27@unibo.it
• Phone: 00390512144666

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.