Understanding Alzheimer's Disease and Related Dementias in American Samoa
ADRD Prevalence in American Samoa
This study is trying to find out how common Alzheimer's Disease and related dementias are among Samoans aged 50 and older, while also looking at their cognitive health and genetic factors.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1098 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | American Samoa Community Cancer Coalition Academic / other |
| Locations | 2 sites (Pago Pago and 1 other locations) |
| Trial ID | NCT05924529 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the prevalence of Alzheimer's Disease and Related Dementias (ADRD) among the Samoan population aged 50 and older. Participants will undergo cognitive assessments to evaluate their cognitive status and will provide blood samples for genetic and plasma biomarker analysis. The study will utilize culturally adapted instruments and the Uniform Data Set from the National Institute on Aging to ensure accurate prevalence data. Additionally, the study will explore factors related to ADRD resilience and vulnerability within this community.
Who should consider this trial
Good fit: Ideal candidates for this study are Samoans aged 50 and older who are community-dwelling and can communicate in English or Samoan.
Not a fit: Patients residing in assisted living or skilled nursing facilities, or those with unstable medical conditions or psychiatric diagnoses, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the prevalence and risk factors of ADRD in the Samoan population, potentially guiding future interventions.
How similar studies have performed: While studies on ADRD prevalence exist, this specific focus on the Samoan population using culturally adapted methods is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 50 or older * Community dwelling * Speaks English or Samoan * Willing to contribute a biomarker specimen Exclusion Criteria: * Residing in Assistant Living or Skilled Nursing Facility * Axis 1 Psychiatric diagnosis (e.g., Schizophrenia, Bipolar) * Unstable medical condition (i.e., metastatic cancer) that could preclude completion of study visit
Where this trial is running
Pago Pago and 1 other locations
- Malaloa GHC Reid Building — Pago Pago, American Samoa (Recruiting)
- Sa'o Fetalai Building — Pago Pago, American Samoa (Recruiting)
Study contacts
- Principal investigator: Va'atausili Tofaeono, MS — American Samoa Community Cancer Coalition
- Study coordinator: Siumu Fa'ai'uaso, BS
- Email: sfaaiuaso@cancercoalition.as
- Phone: 1-684-699-0110
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.