Understanding albumin use in heart surgery patients
Albumin Utilization for Intravascular Volume Replacement in Adult Cardiac Surgical Patients : a Multi-centre, Retrospective, Cohort Study
University Health Network, Toronto · NCT06322537
This study looks at how and when doctors use albumin and other fluids in adults having heart surgery to better understand current practices and improve future care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | University Health Network, Toronto (other) |
| Locations | 10 sites (New Westminster, British Columbia and 9 other locations) |
| Trial ID | NCT06322537 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze the usage patterns of crystalloids and albumin in adult patients undergoing cardiac surgery. By examining data from multiple centers, the study will gather detailed information on when and how albumin is administered during the perioperative period, including its use during cardiopulmonary bypass and in recovery settings. The findings will help identify current practices and inform future research on fluid management in cardiac surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are undergoing cardiac surgery, with or without the use of cardiopulmonary bypass.
Not a fit: Patients who are not undergoing cardiac surgery or are under 18 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could optimize fluid management practices in cardiac surgery, potentially improving patient outcomes.
How similar studies have performed: While there have been studies on fluid management in surgery, this specific focus on albumin use in cardiac surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult (≥18 years old) * Cardiac surgery with the use of cardiopulmonary bypass * Cardiac surgery without the use of cardiopulmonary bypass Exclusion Criteria * None
Where this trial is running
New Westminster, British Columbia and 9 other locations
- Royal Columbian Hospital — New Westminster, British Columbia, Canada (RECRUITING)
- Vancouver General Hospital — Vancouver,, British Columbia, Canada (RECRUITING)
- Nova Scotia Health Authority — Halifax, Nova Scotia, Canada (RECRUITING)
- McMaster University Medical Centre — Hamilton, Ontario, Canada (RECRUITING)
- Kingston Health Sciences Centre — Kingston, Ontario, Canada (NOT_YET_RECRUITING)
- London Health Science Centre — London, Ontario, Canada (RECRUITING)
- University of Ottawa Heart Institute — Ottawa, Ontario, Canada (RECRUITING)
- Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada (RECRUITING)
- St. Michael's Hospital — Toronto, Ontario, Canada (RECRUITING)
- Toronto General Hospital - University Health Network — Toronto, Ontario, Canada (NOT_YET_RECRUITING)
Study contacts
- Principal investigator: Keyvan Karkouti, MD MSc FRCPC — Toronto General Hospital - University Health Network
- Study coordinator: Justyna Bartoszko, MD MSc FRCPC
- Email: actu@uhn.ca
- Phone: 416-340-4800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cardiovascular Surgical Procedures, Albumin