Understanding albumin use in adult cardiac surgery patients
Albumin Utilization for Intravascular Volume Replacement in Adult Cardiac Surgical Patients : a Multicentre Prospective Cohort Study
This study looks at how albumin and other fluids are used during heart surgery to see if different practices affect patient recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | University Health Network, Toronto Academic / other |
| Locations | 2 sites (Kingston, Ontario and 1 other locations) |
| Trial ID | NCT06395480 on ClinicalTrials.gov |
What this trial studies
This multicentre prospective cohort study aims to analyze the usage patterns of crystalloids and albumin in adult patients undergoing cardiac surgery. By observing 100 patients across multiple sites, the study seeks to gather data on the timing, formulation, and dosage of albumin and other blood products used during the perioperative period. The findings will help identify variations in resuscitation practices and their impact on patient outcomes, ultimately informing the design of a larger randomized controlled trial. This research addresses significant knowledge gaps in perioperative blood product management in cardiac surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients aged 18 and older who are scheduled for cardiac surgery.
Not a fit: Patients who are unable to consent or refuse participation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved guidelines for the use of albumin in cardiac surgery, enhancing patient outcomes.
How similar studies have performed: While this study is observational and aims to gather preliminary data, similar studies have indicated variability in blood product management, suggesting potential for impactful findings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All adult (≥18 years old) patients undergoing cardiac surgery (with or without the use of cardiopulmonary bypass) will be eligible. Exclusion Criteria: * Patients who are unable to consent to the study or who refuse participation will be excluded.
Where this trial is running
Kingston, Ontario and 1 other locations
- Kingston Health Sciences Centre — Kingston, Ontario, Canada (Recruiting)
- Toronto General Hospital - University Health Network — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Keyvan Karkouti, MD MSc FRCPC — Toronto General Hospital - University Health Network
- Study coordinator: Justyna Bartoszko, MD MSc FRCPC
- Email: actu@uhn.ca
- Phone: 416-340-4800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.