Umbilico-uterine trunk clipping to lower blood loss during laparoscopic myomectomy
Official title: Reducing Operative Blood Loss in Laparoscopic Myomectomy With Umbilico-uterine Trunk Clipping
Run by Minia University · NCT07200778 · Data updated 2026-11-12
This will test whether temporarily clipping the umbilico-uterine trunk plus local epinephrine reduces bleeding during laparoscopic myomectomy in women aged 19–45 with up to four fibroids.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 19 Years to 45 Years |
| Sex | Women only |
| Enrollment | 66 (estimated) |
| Sponsor | Minia University Academic / other |
| Locations | 1 site (Minya) |
| Status | Recruiting |
| Started | September 11, 2025 |
| Main results expected | March 11, 2026 |
| Study ends | March 11, 2026 |
| Registry record updated | October 7, 2025 |
| Trial ID | NCT07200778 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 19–45 planning laparoscopic myomectomy with no more than four fibroids and a largest fibroid ≤9 cm who are willing to consent and comply with follow-up are ideal candidates.
✕Probably not a fit
Patients who are postmenopausal, have dominant pedunculated subserosal or submucosal fibroids, suspected uterine or adnexal malignancy, or significant medical/psychiatric conditions are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Women aged 19–45 scheduled for laparoscopic myomectomy for up to four fibroids (largest ≤9 cm) will undergo surgery in which the umbilico-uterine trunk is temporarily clipped and local epinephrine infiltration is used per protocol. Surgical teams will record intraoperative blood loss, transfusion requirement, operative time, and immediate complications. Outcomes will be compared to standard expectations to see if the clipping approach lowers perioperative bleeding and related interventions. Patients with submucosal or dominant pedunculated fibroids, postmenopausal status, suspected malignancy, or major comorbidities are excluded.
Why it matters
Potential benefit: If successful, the technique could reduce operative blood loss and lower the need for transfusions and other bleeding-related interventions.
How similar studies have gone: Related methods such as temporary uterine artery occlusion, tourniquets, and local vasoconstrictors have shown reductions in myomectomy blood loss, but direct evidence specifically for umbilico-uterine trunk clipping is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 19 and 45 * Symptoms of menorrhagia, pelvic pain, or infertility * Plan to have a laparoscopic myomectomy * Number of myomas ≤ 4, with the largest myoma measuring ≤ 9 cm Exclusion Criteria: * Postmenopausal status * Dominant pedunculated subserosal FIGO classification (6-7) * Submucosal type of myoma FIGO classification (0-2) * Suspicion of malignant uterine or adnexal diseases * Major medical comorbidities or psychiatric illnesses that could affect follow-up and/or compliance * Refusal to participate or provide consent to the procedures.
Where it's running
-
Minia advanced laparoscopy unit
Minya, Egypt Recruiting
Study contacts
- Study coordinator: Mohamed abdelghfar, Lecturer
- Email: mohamedeleboany@gmail.com
- Phone: +20 10 61624335
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Temporary Uterine Tourniquet vs Local Myometrial Epinephrine During Laparoscopic Myomectomy
This study tests whether a temporary uterine tourniquet works better or worse than injecting epinephrine into the uterine muscle to control blood loss during laparoscopic myomectomy in women with uterine fibroids.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.