Ultrasound screening and combined treatment strategies for people with coronary and neck artery narrowing.
A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery Stenosis
This project uses Doppler ultrasound to screen people with coronary artery disease scheduled for elective PCI to see if finding and managing neck artery narrowings together with heart procedures leads to better outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Beijing Anzhen Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Trial ID | NCT07034157 on ClinicalTrials.gov |
What this trial studies
This is a prospective observational cohort enrolling adults with coronary artery disease who are scheduled for elective percutaneous coronary intervention at Beijing Anzhen Hospital. Participants receive Doppler ultrasound screening of head and neck arteries the day before PCI to document any cervicocephalic arterial stenosis and its severity. The study records which management approach is used—observation, cerebrovascular intervention such as carotid stenting, or combined procedures—and tracks clinical outcomes including stroke, cardiac events, and death. Data will provide real-world information on the prevalence of concurrent stenosis and the associations between different integrated treatment strategies and patient outcomes.
Who should consider this trial
Good fit: Adults aged 18 and older with coronary artery disease who are scheduled for elective percutaneous coronary intervention and expected to survive at least one year are ideal candidates.
Not a fit: People who are not having PCI, have an expected survival under one year, or have other serious concurrent illnesses are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the findings could help doctors spot and treat dangerous neck artery narrowings in people having PCI, potentially reducing stroke and other complications.
How similar studies have performed: Previous observational studies and limited interventional research have linked carotid and coronary disease and suggest potential benefit from combined care, but randomized evidence on integrated screening-and-treatment pathways remains limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥18 years; 2. Patients with coronary artery disease scheduled to undergo elective percutaneous coronary intervention (PCI) on the following day. Exclusion Criteria: 1. The expected survival is less than 1 years; 2. Simultaneously merge other serious diseases;
Where this trial is running
Beijing
- Beijing Anzhen Hospital — Beijing, China (Recruiting)
Study contacts
- Study coordinator: Xiaochuan Huo, M.D.
- Email: huoxiaochuan@126.com
- Phone: +8613716292262
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.