Ultrasound of abdominal breathing muscles in Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational, cross-sectional study enrolling adults with Parkinson's disease at Hoehn and Yahr stages 1–3. Investigators will use ultrasonography to measure thickness of rectus abdominis, transversus abdominis, and oblique muscles and will record maximal inspiratory and expiratory pressures (MIP and MEP). Disease severity will be captured with standardized clinical scales and cognitive screening will ensure participants can follow instructions. The study will compare muscle thickness with expiratory strength and clinical severity to identify patterns that could inform respiratory rehabilitation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years
* Parkinson's disease diagnosis with Modified Hoehn and Yahr stages 1-2-3
* Mini-Mental State Examination (MMSE) score \> 23
* Body Mass Index (BMI) \< 30

Exclusion Criteria:

* Active smokers
* Individuals with a diagnosis of active chest disease
* Those with hemodynamic instability
* Individuals with unstable vital signs
* Parkinson's patients who cannot be controlled with medical treatment
* Parkinson Plus syndromes

Where it's running

• İstanbul Fizik Tedavi Ve Rehabilitasyon Eğitim Ve Araştirma Hastanesi
  Istanbul, Bahçeli̇evler, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ayşe Nur Sarikoç
• Email: aysenuryigit885@gmail.com
• Phone: +905412105141

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.