Ultrasound measurement of airway anatomy in pregnant, preeclamptic, and nonpregnant women
Official title: Clinical and Ultrasonographic Assessment of Airway Indices Among Nonpregnant, Normotensive Pregnant and Pre-eclamptic Patients: a Prospective Observational Study
Run by South Valley University · NCT07423741 · Data updated 2026-11-12
This study will test whether simple ultrasound measurements of the throat can help predict difficult tracheal intubation in nonpregnant women, women with normal pregnancy, and women with preeclampsia having surgery under general anesthesia.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | Women only |
| Enrollment | 180 (estimated) |
| Sponsor | South Valley University Academic / other |
| Locations | 1 site (Qina, Qena Governorate) |
| Status | Recruiting |
| Started | December 15, 2024 |
| Main results expected | November 2026 |
| Study ends | December 2026 |
| Registry record updated | February 20, 2026 |
| Trial ID | NCT07423741 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women of childbearing age who are nonpregnant or who are pregnant (≥32 weeks) and either normotensive or diagnosed with preeclampsia, who are scheduled for surgery under general anesthesia and do not meet exclusion criteria.
✕Probably not a fit
Patients who are excluded—those with eclampsia, gestation under 32 weeks, BMI over 30 kg/m2, height under 150 cm, or obvious airway abnormalities—would not be eligible and thus would not receive benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will compare clinical airway indices, bedside ultrasound airway measurements, and the laryngoscopic view during direct laryngoscopy among three groups: nonpregnant women of childbearing age, normotensive pregnant women, and pregnant women with preeclampsia. Participants undergoing surgery with general anesthesia will have preoperative clinical airway scores (e.g., Mallampati) and ultrasound parameters recorded, and the Cormack-Lehane grade noted during intubation. Patients with early gestation (<32 weeks), eclampsia, BMI >30 kg/m2, height <150 cm, or obvious anatomical airway problems are excluded. The goal is to see if portable ultrasound adds reliable, noninvasive information to predict difficult laryngoscopy in this population.
Why it matters
Potential benefit: If successful, using ultrasound could allow earlier identification of likely difficult airways and reduce repeated intubation attempts and related complications.
How similar studies have gone: Previous studies have reported promising results for airway ultrasonography in predicting difficult laryngoscopy, but the technique is not yet universally validated or in routine use.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * -normotensive pregnant * pre-eclamptic patients. * nonpregnant females in child bearing period . Exclusion Criteria: * Patients excluded were women at \<32 weeks' gestation or with Eclampsia . * height \<150 cm, body mass index (BMI) \>30 kg/m2 . * predicted airwy difficulty due to any other cause as neck swelling , facial deformity and prominent teeth.
Where it's running
-
Qena University
Qina, Qena Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Zeinab M Sayed, MD
- Email: zeinab5aton@gmail.com
- Phone: 01009071365
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.