Ultrasound imaging to study fibrotic tissue in knee and shoulder joints
Ultrasound Imaging of Fibrotic Tissue Using Machine Learning
This study is testing how ultrasound can help us understand and treat stiff, fibrous tissue in the knee and shoulder joints to improve recovery for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Peking University Third Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Trial ID | NCT05818904 on ClinicalTrials.gov |
What this trial studies
This project aims to collect ultrasonic spectrum information from fibrotic tissue in the shoulder and knee joints. By utilizing machine learning, the study will investigate the mechanisms of ultrasound imaging of fibrosis and develop a model to establish the relationship between joint stiffness and fibrosis formation. The ultimate goal is to create a method for ultrasonic localization and evaluation of joint fibrosis, which could lead to new conservative treatment methods and improved surgical positioning. This research seeks to reduce the occurrence of joint fibrosis and enhance patient recovery and functionality.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with unilateral shoulder or knee joint stiffness lasting more than three months.
Not a fit: Patients with non-healing wounds, joint dislocations, or other conditions that prevent ultrasound examination will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and treatment methods for patients suffering from joint stiffness due to fibrosis.
How similar studies have performed: While this approach is innovative, similar studies utilizing ultrasound imaging for fibrotic tissue have shown promise in other contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Unilateral shoulder or knee joint stiffness and normal on the opposite side 2. The course of the disease is longer than 3 months 3. Good cognitive function, able to understand the content of this experiment, willing to cooperate with follow-up 4. Over 18 years old, voluntarily participate in this study, and sign the informed consent Exclusion Criteria: 1. Wound non-healing, joint dislocation or unstable fracture fixation, pseudarthrosis, joint purulent infection and other contraindications for joint range of motion examination 2. There are skin lesions, wounds or allergies to the coupling agent on the joint surface and other conditions that cannot be used for ultrasound examination
Where this trial is running
Beijing
- Peking University Third Hospital — Beijing, China (Recruiting)
Study contacts
- Study coordinator: Buwen Yao, PhD
- Email: buwenyao@gmail.com
- Phone: 15600555851
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.