Ultrasound-Guided Saline Injections to Prevent Tendon Scar After Finger Tendon Repair

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center randomized trial enrolling 80 adults aged 18–60 undergoing zone II flexor tendon repair. Participants are assigned 1:1 to receive standard postoperative rehabilitation with or without ultrasound-guided injections of 1 mL normal saline at the adhesion site on days 7, 14, and 21. Dynamic ultrasound will track saline distribution, and follow-up visits occur at 6 weeks and 3 months to measure total active motion in the repaired digits. The primary outcome is TAM at 3 months, analyzed as a continuous measure. Safety monitoring will assess adverse events related to injections.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18 to 60 years.
2. Zone II flexor tendon rupture in the index, middle, ring, or little finger.
3. Scheduled to undergo tendon repair surgery.

Exclusion Criteria:

1. Concomitant irreparable vascular and/or nerve injury.
2. History of diabetes mellitus.
3. History of treatment with nonsteroidal anti-inflammatory drugs.
4. History of cardiac insufficiency.
5. History of hematologic disease.
6. History of hepatic or renal dysfunction.
7. History of rheumatic or autoimmune disease.
8. History of chemotherapy or radiotherapy.
9. History of steroid treatment.
10. Pregnancy.
11. Concurrent participation in another clinical trial.

Where it's running

• Shanghai sixth people's hospital
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Kai Wang, MD
• Email: 2019wk@sjtu.edu.cn
• Phone: 86+19821288715

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Virtual reality rehab with early active mobilization after flexor tendon repair

  This study tests whether adding virtual reality–based rehabilitation to an early active mobilization plan helps people recover finger movement, strength, and less pain after flexor tendon repair.

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• Wrist position in a 3D-printed dorsal blocking splint after flexor tendon repair

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• Rehabilitation comparison after thumb flexor tendon repair

  This tests whether starting early active motion or keeping the thumb in a plaster cast for four weeks works better after surgery for a torn thumb flexor tendon in people older than 15.

  Recruiting at 5 sites Karolinska Institutet · Linköping and 4 other locations · NCT06836349

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.