Ultrasound-guided manual vacuum aspiration for managing first trimester miscarriage
Ultrasound-guided Manual Vacuum Aspiration (USG-MVA)
Chinese University of Hong Kong · NCT05413525
This study looks at how well ultrasound-guided manual vacuum aspiration works for women experiencing first trimester miscarriages and whether it can help with further testing.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Chinese University of Hong Kong (other) |
| Locations | 2 sites (Hong Kong, Shatin and 1 other locations) |
| Trial ID | NCT05413525 on ClinicalTrials.gov |
What this trial studies
This observational study reviews the experience of ultrasound-guided manual vacuum aspiration (USG-MVA) in Hong Kong, focusing on its effectiveness in managing first trimester miscarriages. The study evaluates how USG-MVA can facilitate cytological analysis, which is often challenging after medical evacuation. The procedure uses a hand-held syringe to create suction and can be performed in an outpatient setting with minimal sedation. The investigators have previously established the feasibility and acceptability of this method, having conducted over 200 cases since its introduction in 2015.
Who should consider this trial
Good fit: Ideal candidates include women aged 18 and above who are experiencing a first trimester miscarriage and are suitable for USG-MVA.
Not a fit: Patients with cervical stenosis, significant uterine abnormalities, or those unable to tolerate pelvic examinations may not benefit from this procedure.
Why it matters
Potential benefit: If successful, this approach could provide a safer and more effective option for women experiencing first trimester miscarriages.
How similar studies have performed: Previous studies have shown that ultrasound-guided manual vacuum aspiration is an effective alternative to traditional surgical methods, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women 18 years old or above * Women with miscarriage who are suitable candidates for USG-MVA * first trimester delayed miscarriage ≤ 12 weeks of gestation * incomplete miscarriage with POG ≤ 5cm * hemodynamically stable * tolerates well with speculum examination Exclusion Criteria: * Women who are not feasible for the USG-MVA * cervical stenosis * fibroid uterus ≥12 weeks in size * known uterine malformation * bleeding disorder * suspicion of active infection * inability to tolerate pelvic examination * History of allergy to misprostol or same group of medications
Where this trial is running
Hong Kong, Shatin and 1 other locations
- Chinese University of Hong Kong — Hong Kong, Shatin, Hong Kong (RECRUITING)
- Union Hospital — Hong Kong, Hong Kong (RECRUITING)
Study contacts
- Study coordinator: Jacqueline Pui Wah Chung
- Email: jacquelinechung@cuhk.edu.hk
- Phone: +852 3505 1537
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ultrasound-guided Manual Vacuum Aspiration, First Trimester Spontaneous Abortion, USG-MVA, Ultrasound-guided manual vacuum aspiration, Miscarriage, Cytological analysis, Manual vacuum aspiration