Ultrasound-guided core needle biopsy to stage bladder urothelial carcinoma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational feasibility study in which patients scheduled for radical cystectomy undergo an ultrasound-guided core needle biopsy of the bladder tumor prior to surgery. Biopsy specimens are processed and interpreted by pathology and compared with the final surgical pathology from the cystectomy to determine concordance in stage and sampling adequacy. The study will record procedure feasibility, diagnostic yield, and any immediate complications related to the biopsy. Conducted at Mayo Clinic in Rochester, the protocol uses prior abdominal imaging to guide biopsy planning and targeting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Undergoing radical cystectomy for confirmed or suspected urothelial carcinoma of the bladder
* Prior abdominal imaging

Exclusion Criteria:

* History of partial cystectomy or complex bladder reconstruction or substitution (i.e. bladder augment or urothelial recurrence in a neobladder)

Where it's running

• Mayo Clinic in Rochester
  Rochester, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Vidit Sharma, MD — Mayo Clinic in Rochester
• Study coordinator: Hosanna Yeadon, BA
• Email: biffert.hosanna@mayo.edu
• Phone: 507-538-5019

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.