Ultrasound guided blood injection for jaw joint dislocation

Ultrasound -Guided Versus Conventional Non Guided Autologous Blood Injection For Treatment of Patients With Chronic Recurrent Temporomandibular Joint Dislocation. A Randomized Clinical Trial

Not applicable Interventional Cairo University · NCT06244134

This study is testing whether using ultrasound to guide a blood injection helps people with chronic jaw joint dislocation feel better compared to a regular injection method.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years and up
SexAll
SponsorCairo University Academic / other
Locations1 site (Cairo)
Trial IDNCT06244134 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effectiveness of ultrasound-guided autologous blood injection versus a non-guided technique for treating chronic recurrent temporomandibular joint dislocation. Patients will be randomly assigned to receive either the ultrasound-guided injection or the standard injection based on anatomical landmarks. The procedure involves withdrawing blood from the patient's arm and injecting it into the joint space and surrounding tissue under local anesthesia. The goal is to determine which method provides better outcomes for patients experiencing this condition.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who have experienced at least three episodes of temporomandibular joint dislocation in the past six months.

Not a fit: Patients with inflammatory joint diseases, bleeding disorders, or those who have had recent fractures or surgeries in the temporomandibular joint may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to more effective treatment options for patients suffering from temporomandibular joint dislocation.

How similar studies have performed: While this approach is relatively novel, similar studies using ultrasound guidance in other joint injections have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient with at least 3 episodes of temporomandibular joint dislocation in the past 6 months.
* Necessitating a visit to the emergency room or trained professional to reduce the dislocation.
* Radiological evidence of displacement of condylar head beyond the articular eminence on wide mouth opening.
* Maximum mouth opening (MMO) more than 40 mm.
* Unilateral or bilateral.
* Over 18 years of age.
* Both gender Males or females.

Exclusion Criteria:

* Patient having inflammatory temporomandibular joint disease like tuberculous arthritis, rheumatoid arthritis.
* Patients with bleeding disorders, pregnancy or bony pathology of temporomandibular joint .
* Allergy to local anesthetic.
* Severe epilepsy or Parkinson's disease.
* Patient on anti-depressants or anti-psychotics.
* Inability to follow-up the patient during the entire follow-up period.
* Patients who had recent fracture at temporomandibular joint level or who had previous surgical interference to temporomandibular joint .
* Refused to sign the written informed consent were also excluded.
* Dystonia

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Temporomandibular Joint Dislocationultrasoundautologous bloodtemporomandibular jointdislocation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.