Ultrafast ultrasound to assess diaphragm function
Ultrafast Ultrasound for the Functional Assessment of the Diaphragm: Agreement With Standards Mechanical and Electrophysiological Variables and Diagnosis Performance
This study is testing a new ultrasound method to see if it can help doctors understand how well the diaphragm is working in patients with diaphragm problems.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Institut de Myologie, France Academic / other |
| Locations | 1 site (Paris) |
| Trial ID | NCT05265351 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of ultrafast ultrasound imaging to evaluate diaphragm function in patients with diaphragm dysfunction. It aims to establish relationships between ultrasound-derived indices and diaphragm electromyography (EMG) as well as transdiaphragmatic pressure measurements. The study will also explore the diagnostic capabilities of ultrafast ultrasound in identifying the causes of diaphragm dysfunction, such as contractility alterations or phrenic nerve conduction defects. By utilizing high frame rate imaging, the research seeks to provide a non-invasive method for assessing diaphragm health.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old with confirmed or suspected diaphragm dysfunction.
Not a fit: Patients with known allergies to latex or Lidocaine, those with pacemakers, or pregnant or nursing women may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved diagnosis and management of diaphragm dysfunction, enhancing patient outcomes.
How similar studies have performed: While the use of ultrafast ultrasound for diaphragm assessment is a novel approach, preliminary findings suggest potential reliability in healthy subjects, warranting further investigation in patients.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \> 18 years old * Patients with confirmed diaphragm dysfunction or suspicion * Written informed consent * Able to comply with all protocol requirements * Affiliate or beneficiary of a social security scheme Exclusion Criteria: * Known allergy to latex * Known allergy to Lidocaine or similar product * Pacemaker * Guardianship/trusteeship * Pregnant or nursing women
Where this trial is running
Paris
- Département R3S - Hôpital Pitié-Salpêtrière — Paris, France (Recruiting)
Study contacts
- Principal investigator: Damien BACHASSON, PhD — Institute ofMyology
- Study coordinator: Damien BACHASSON, PhD
- Email: d.bachasson@institut-myologie.org
- Phone: 01 42 16 66 43
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.