Clinical trial No longer in our active list Interventional Ages 18 and up

Ultrafast ultrasound to assess diaphragm function

Official title: Ultrafast Ultrasound for the Functional Assessment of the Diaphragm: Agreement With Standards Mechanical and Electrophysiological Variables and Diagnosis Performance

Run by Institut de Myologie, France · NCT05265351 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing a new ultrasound method to see if it can help doctors understand how well the diaphragm is working in patients with diaphragm problems.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorInstitut de Myologie, France
Academic / other
Locations1 site (Paris)
Trial IDNCT05265351 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults over 18 years old with confirmed or suspected diaphragm dysfunction.

Probably not a fit

Patients with known allergies to latex or Lidocaine, those with pacemakers, or pregnant or nursing women may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of ultrafast ultrasound imaging to evaluate diaphragm function in patients with diaphragm dysfunction. It aims to establish relationships between ultrasound-derived indices and diaphragm electromyography (EMG) as well as transdiaphragmatic pressure measurements. The study will also explore the diagnostic capabilities of ultrafast ultrasound in identifying the causes of diaphragm dysfunction, such as contractility alterations or phrenic nerve conduction defects. By utilizing high frame rate imaging, the research seeks to provide a non-invasive method for assessing diaphragm health.

Why it matters

Potential benefit: If successful, this approach could lead to improved diagnosis and management of diaphragm dysfunction, enhancing patient outcomes.

How similar studies have gone: While the use of ultrafast ultrasound for diaphragm assessment is a novel approach, preliminary findings suggest potential reliability in healthy subjects, warranting further investigation in patients.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \> 18 years old
* Patients with confirmed diaphragm dysfunction or suspicion
* Written informed consent
* Able to comply with all protocol requirements
* Affiliate or beneficiary of a social security scheme

Exclusion Criteria:

* Known allergy to latex
* Known allergy to Lidocaine or similar product
* Pacemaker
* Guardianship/trusteeship
* Pregnant or nursing women

Where it's running

  • Département R3S - Hôpital Pitié-Salpêtrière
    Paris, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.