Ultra-translucent multi-layer zirconia versus lithium disilicate laminate veneers for front teeth
Clinical Performance of Ultra-translucent Multi-layer Monolithic Zirconia and Lithium Disilicate Ceramic Laminate Veneers
This compares ultra-translucent zirconia and lithium disilicate laminate veneers in adults (18–50) needing cosmetic anterior veneers to see if one gives better fit, appearance, and patient satisfaction.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 10 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT07113873 on ClinicalTrials.gov |
What this trial studies
This randomized interventional trial will assign eligible adult patients to receive either ultra-translucent multi-layer monolithic zirconia or lithium disilicate ceramic laminate veneers and follow clinical performance and patient satisfaction over time. The protocol emphasizes minimally invasive enamel preparation for anterior teeth and standardized bonding procedures, with known bonding challenges for zirconia addressed using air abrasion and 10-MDP–based primers and cements. Outcomes include clinical performance measures and patient-reported satisfaction at scheduled follow-ups. Participants must meet oral health and enamel criteria and commit to clinic visits at Cairo University.
Who should consider this trial
Good fit: Adults aged 18–50 with good oral and periodontal health, adequate enamel for bonding, no bruxism, and a clear cosmetic indication (diastema, mild discoloration, or minor shape/size changes) who can attend follow-up visits are ideal candidates.
Not a fit: People with poor oral hygiene, active periodontal disease, bruxism or other dysfunctional habits, high caries risk, insufficient enamel for bonding, or extreme dental staining are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the results could help dentists choose a veneer material that gives better-looking, durable, minimally invasive restorations and clearer guidance on bonding protocols.
How similar studies have performed: Recent laboratory and short-term clinical reports suggest similar bond strength and acceptable esthetics for high-translucent zirconia and lithium disilicate when using air abrasion and 10-MDP primers, but long-term randomized comparisons are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1- Age between 18 and 50 years. 2. Absence of abnormal functional habits such as bruxism. 3. Good condition of gingival and periodontal tissues. 4. Good oral health. 5. A clear indication for patients for treatment with ceramic laminate veneers: Presence of diastema, moderate discolored dental restorations, slight modification of color in the discolored teeth, and modification of shape and sizes of the teeth. 6\. Patient commitment for attending follow up session Exclusion Criteria: 1. Age under 18 years 2. Bad oral hygiene 3. Dysfunctional habits and bruxism 4. Periodontal diseases 5. High risk of caries 6. Inadequate enamel for bonding 7. Extreme staining and color change in tooth -
Where this trial is running
Cairo
- Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Gihan El naggar Professor, PhD
- Email: gihan.abdelhadyelnaggar@dentistry.cu.edu.eg
- Phone: 01117676668
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.