Clinical trial Recruiting at 1 site Interventional Ages 20 to 40

Tyler Twist versus traditional eccentric wrist extensor exercises for lateral epicondylalgia

Official title: Effects of the Tyler Twist Versus Eccentric Exercises in Patients With Lateral Epicondylagia

Run by Riphah International University · NCT07626632 · Data updated 2026-11-12

This study tests whether the Tyler Twist is better than standard eccentric wrist extensor exercises for reducing elbow pain and improving grip and function in adults with lateral epicondylalgia.

Quick facts

Study typeInterventional
Ages20 Years to 40 Years
SexAll
Enrollment38 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedAugust 1, 2026
Main results expectedOctober 20, 2026
Study endsNovember 13, 2026
Registry record updatedSeptember 24, 2026
Trial IDNCT07626632 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20–40 with subacute to chronic lateral epicondylalgia and positive Cozen’s, Mill’s, or Maudsley tests, and pain during activity with grip or resisted wrist extension.

Probably not a fit

Patients without or with very mild symptoms, acute elbow injury, or those who have had recent corticosteroid injections may see no benefit or be unsuitable.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two exercise approaches for lateral epicondylalgia. Participants with subacute to chronic symptoms will be randomized to perform either Tyler Twist exercises or traditional eccentric wrist extensor exercises. Outcomes include pain during activity, grip strength, and functional measures over a defined treatment period. The Tyler Twist uses a TheraBand FlexBar to provide both eccentric and concentric loading in a controlled, functional manner. Prior evidence suggests benefit from eccentric training, but direct comparisons with Tyler Twist are limited, making this head-to-head trial important for guiding conservative management.

Why it matters

Potential benefit: If successful, patients could experience greater pain relief and improved hand function with the Tyler Twist approach.

How similar studies have gone: Previous studies support eccentric training for tendinopathy; direct head-to-head comparisons with Tyler Twist are limited, so this study addresses a gap in evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ● Males and female patients suffering from lateral epicondylagia in subacute and chronic phase.

  * Age between 20yrs-40yrs.
  * Patients screened with positive Cozen's test, positive Mill's test, positive Maudsley's test \[14\].
  * NPRS pain score ≥ 4 on activity.
  * Tenderness on palpation over the lateral epicondyle of humerus,
  * Pain with gripping, Pain with resisted wrist extension.

Exclusion Criteria:

* History of recent trauma or surgery of elbow.
* Acute stage of lateral epicondylagia.
* Corticosteroid injection within the last 3 months.
* Neurological defeciency of the affected limb \[16\].
* Systemic inflammatory diseases, such as rheumatoid arthritis, lupus, or fibromyalgia.
* Diabetes mellitus (uncontrolled) due to its influence on tendinopathy.

Where it's running

  • Ghurki Hospital Lahore
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.