Tumor deposits at the fusion of the right and left gastric mesenteries after proximal gastrectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational, single-center study will examine surgical specimens from adults with primary gastric adenocarcinoma who undergo proximal gastrectomy with D2 lymphadenectomy plus complete mesogastric excision. Investigators will inspect the fusion site between the right and left gastric mesenteries and document any tumor deposits using standard pathological methods. Eligible patients are clinical stage cT2–4aN0–3M0, aged 18–85, ASA class I–III, without prior neoadjuvant therapy or previous upper abdominal surgery. The study aims to generate evidence on whether current dissection patterns may leave residual tumor at the mesenteric fusion and to inform standardized lymph node clearance recommendations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged older than 18 years and younger than 85 years
2. Primary gastric adenocarcinoma confirmed by preoperative pathology result
3. cT2-4aN0-3M0 at preoperative evaluation according to the American Joint 8 Committee on Cancer (AJCC) Cancer Staging Manual 8th Edition
4. Patients undergoing proximal gastrectomy with D2 lymphadenectomy plus complete mesogastric excision
5. American Society of Anesthesiologists (ASA) class I, II, or III
6. Written informed consent

Exclusion Criteria:

1. Negative preoperative biopsy
2. Too late tumour stage or metastasis (cT4b/M1)
3. BMI\>30 kg/m2
4. previous neoadjuvant chemotherapy or radiotherapy
5. Previous upper abdominal surgery
6. Combined with other malignant diseases
7. Reject operation

Where it's running

• Department of Gastrointestinal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Tao Wang, Ph.d
• Email: 15002740874@163.com
• Phone: +86-197-068-25286

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.