Treatment patterns for managing high blood pressure in Brazil's public primary care system
Official title: Clinical Landscape of Epidemiology and Assessment of Results in Hypertension
Run by AstraZeneca · NCT07361276 · Data updated 2026-11-12
This project uses past medical records to see how adults with high blood pressure are treated in Brazil's public primary care system.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 15000 (estimated) |
| Sponsor | AstraZeneca Industry-sponsored |
| Locations | 1 site (Florianópolis) |
| Status | Recruiting |
| Started | March 31, 2026 |
| Main results expected | November 30, 2026 |
| Study ends | November 30, 2026 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT07361276 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with a recorded hypertension diagnosis or at least two consecutive high blood pressure readings in the participating municipalities' EMRs and with at least six months of continuous follow-up in the same municipality are the ideal candidates for inclusion.
✕Probably not a fit
People whose records are incomplete, not traceable, or who receive care outside the participating municipalities are excluded and unlikely to benefit directly from this analysis.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This retrospective observational cohort uses routinely collected electronic health records from five Brazilian municipalities participating in the epHealth Primary Care Solutions platform to characterize treatment patterns for hypertension. Adults (≥18) will be identified by recorded hypertension diagnoses or by at least two consecutive blood pressure measurements ≥140/90 mmHg within 30 days and followed for a minimum of six months. Primary outcomes focus on diagnostic and therapeutic clinical inertia, including timing of treatment changes and alignment with national guideline recommendations rather than testing an intervention. The design leverages existing EMR data to capture real-world practice across diverse socio-demographic and healthcare settings within Brazil's public primary care system.
Why it matters
Potential benefit: If successful, the findings could reveal gaps and delays in hypertension care and guide changes to improve blood pressure control across Brazil's public primary care system.
How similar studies have gone: Similar retrospective analyses of electronic health records have previously documented clinical inertia and treatment gaps in hypertension care, so the approach is well-established though findings vary by setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years at the time of Hypertension diagnosis * Hypertension diagnosis as retrieved from registered ICD codes or CIAP Codes (primary care codes) in the EMR , OR At least two blood pressure measurements ≥140/90 mmHg during the study period. The blood measurements should be consecutive and obtained within a 30 days period. * Continuous follow-up in the same municipality for at least 6 months after index measurement. * Availability of structured EMR data including clinical encounters, diagnoses, and prescriptions Exclusion Criteria: \- Patients with incomplete data or not traceable in the registration systems
Where it's running
-
Research Site
Florianópolis, Brazil Recruiting
Study contacts
- Principal investigator: Julia Machline Carrion, Medical — EpHealth Soluções em Tecnologia da Informação Ltda
- Study coordinator: AstraZeneca Clinical Study Information Center
- Email: information.center@astrazeneca.com
- Phone: 1-877-240-9479
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.