Treatment outcomes of selective laryngeal reinnervation for vocal fold paralysis
Official title: Selective Laryngeal Reinnervation for Bilateral Vocal Fold Paralysis
Run by Weill Medical College of Cornell University · NCT03980275 · Data updated 2026-11-12
This study is testing if a specific surgery can help people with vocal fold paralysis regain their voice and reduce complications after not improving for at least six months.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | Weill Medical College of Cornell University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | December 10, 2019 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2030 |
| Registry record updated | April 21, 2026 |
| Trial ID | NCT03980275 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18-70 with bilateral vocal fold paralysis who have not shown improvement for six months.
✕Probably not a fit
Patients with severe respiratory compromise or those with certain medical implants may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the outcomes of selective laryngeal reinnervation procedures in patients suffering from bilateral vocal fold paralysis. It aims to assess the effectiveness of this surgical intervention in improving vocal function and reducing complications associated with the condition. The study will include patients aged 18-70 who have not experienced improvement in their condition for at least six months. By closely monitoring these patients, the study seeks to gather valuable data on the long-term benefits and potential risks of the procedure.
Why it matters
Potential benefit: If successful, this approach could significantly improve vocal function and quality of life for patients with bilateral vocal fold paralysis.
How similar studies have gone: While this approach is being explored, similar studies have shown promise in improving outcomes for patients with vocal fold paralysis.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18-70 * Patients with bilateral vocal fold paralysis without any improvement for 6 months Exclusion Criteria: * Patients with neck or chest radiation * Patients with severe respiratory compromise * Patients with cricoarytenoid ankylosis * Patients with pacemakers * Patients who are pregnant * Patients with cochlear implant, or any nerve stimulator implants
Where it's running
-
Sean Parker Institute for the Voice
New York, New York, United States Recruiting
Study contacts
- Principal investigator: Babak Sadoughi, MD — Weill Medical College of Cornell University
- Study coordinator: Babak Sadoughi, MD
- Email: bas9049@med.cornell.edu
- Phone: 646-962-4712
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Implant for treating vocal cord paralysis
This study is testing a new implant to see if it can safely help people with vocal cord paralysis speak better.
-
Evaluating vocal fold motion in children on noninvasive ventilation
This study is testing if using ultrasound can safely check how well the vocal folds are moving in kids on noninvasive ventilation in the ICU compared to a standard method that might be riskier.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.