Treatment options for full thickness macular holes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the management of full thickness macular holes (FTMH), a condition that leads to central vision loss. It compares the outcomes of sequential cataract surgery followed by vitrectomy against a combined phaco-vitrectomy approach. The study aims to determine the optimal timing and method for surgical intervention to improve visual outcomes while minimizing complications. Patients with varying durations of symptoms will be included to assess the effectiveness of these surgical strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Idiopathic full thickness macular hole
* Duration of symptoms of \<30 days for Group 1 and 2
* Duration of symptoms of 3-12 months for Group 3
* FTMH size \<400µm
* \>18 years
* Able to give informed consent
* Compliance for postoperative positioning

Exclusion Criteria:

* High myopia (≤-3)
* Traumatic macular hole
* Prior ocular surgery, including cataract surgery
* Other ocular diseases compromising the visual acuity (i.e., AMD, diabetic retinopathy, previous vein occlusion)
* Posterior vitreous detachment (Weiss ring)

Where it's running

• Rigshospitalet, Denmark
  Glostrup Municipality, Copenhagen, Denmark Recruiting

Study contacts

• Principal investigator: Morten Dornonville de la Cour, MD, Prof. — Copenhagen University Hospital, Rigshospitalet
• Study coordinator: Asrin Rasul, MD
• Email: asrin.rasul@regionh.dk
• Phone: 004522365420

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.