Clinical trial Recruiting at 4 sites Observational Ages 18 to 100

Treatment options for Barrett's Esophagus and related cancer

Official title: A Multicenter Prospective Study Evaluating Outcomes of Endoscopic Eradication Therapy in Patients With Barrett's Esophagus Associated Neoplasia: The TREAT-BE (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus) Consortium

Run by University of Colorado, Denver · NCT02634645 · Data updated 2026-11-12

This study is looking at how well different treatments work for people with Barrett's esophagus and esophageal cancer to help improve their health and quality of life.

More Esophageal Cancer trials

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment5000 (estimated)
SponsorUniversity of Colorado, Denver
Academic / other
Locations4 sites (Los Angeles, California and 3 other locations)
StatusRecruiting
StartedJanuary 2015
Main results expectedJanuary 2027
Study endsJanuary 2027
Registry record updatedFebruary 28, 2025
Trial IDNCT02634645 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients diagnosed with Barrett's esophagus-related neoplasia or dysplasia and those with esophageal cancer.

Probably not a fit

Patients with squamous cell carcinoma will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates patients with Barrett's esophagus and esophageal cancer who are being considered for endoscopic eradication therapy. Participants will be enrolled at various gastrointestinal clinics and endoscopy suites, where their demographics, risk factors, and health-related quality of life will be assessed. Data will be collected on previous treatments, endoscopic evaluations, and any complications from surgeries or therapies. The study aims to document outcomes related to endoscopic and surgical interventions for Barrett's esophagus and associated neoplasia.

Why it matters

Potential benefit: If successful, this study could improve treatment strategies and outcomes for patients with Barrett's esophagus and esophageal cancer.

How similar studies have gone: Other studies have shown promise in using endoscopic eradication therapies for Barrett's esophagus, indicating a potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with Barrett's related neoplasia and dysplasia. Patients with esophageal cancer

Exclusion Criteria:

* Patients with squamous cell carcinoma

Where it's running

  • UCLA Medical Center
    Los Angeles, California, United States
    Recruiting
  • Moffitt Cancer Center
    Tampa, Florida, United States
    Recruiting
  • Northwestern Memorial Hospital
    Chicago, Illinois, United States
    Recruiting
  • Washington University
    St Louis, Missouri, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.