Treatment options for Barrett's Esophagus and related cancer
Official title: A Multicenter Prospective Study Evaluating Outcomes of Endoscopic Eradication Therapy in Patients With Barrett's Esophagus Associated Neoplasia: The TREAT-BE (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus) Consortium
Run by University of Colorado, Denver · NCT02634645 · Data updated 2026-11-12
This study is looking at how well different treatments work for people with Barrett's esophagus and esophageal cancer to help improve their health and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | University of Colorado, Denver Academic / other |
| Locations | 4 sites (Los Angeles, California and 3 other locations) |
| Status | Recruiting |
| Started | January 2015 |
| Main results expected | January 2027 |
| Study ends | January 2027 |
| Registry record updated | February 28, 2025 |
| Trial ID | NCT02634645 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with Barrett's esophagus-related neoplasia or dysplasia and those with esophageal cancer.
✕Probably not a fit
Patients with squamous cell carcinoma will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates patients with Barrett's esophagus and esophageal cancer who are being considered for endoscopic eradication therapy. Participants will be enrolled at various gastrointestinal clinics and endoscopy suites, where their demographics, risk factors, and health-related quality of life will be assessed. Data will be collected on previous treatments, endoscopic evaluations, and any complications from surgeries or therapies. The study aims to document outcomes related to endoscopic and surgical interventions for Barrett's esophagus and associated neoplasia.
Why it matters
Potential benefit: If successful, this study could improve treatment strategies and outcomes for patients with Barrett's esophagus and esophageal cancer.
How similar studies have gone: Other studies have shown promise in using endoscopic eradication therapies for Barrett's esophagus, indicating a potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with Barrett's related neoplasia and dysplasia. Patients with esophageal cancer Exclusion Criteria: * Patients with squamous cell carcinoma
Where it's running
-
UCLA Medical Center
Los Angeles, California, United States Recruiting -
Moffitt Cancer Center
Tampa, Florida, United States Recruiting -
Northwestern Memorial Hospital
Chicago, Illinois, United States Recruiting -
Washington University
St Louis, Missouri, United States Recruiting
Study contacts
- Principal investigator: Sachin Wani, MD — University of Colorado, Denver
- Study coordinator: Sachin Wani, MD
- Email: sachin.wani@ucdenver.edu
- Phone: 720-848-2786
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.