Treatment of onychomycosis using laser and topical medication
Combined Fractional CO2 Laser With Topical Tioconazole Versus Q-switched Nd:YAG Laser in the Treatment of Onychomycosis; a Randomized Controlled Trial
This study is testing if using a laser treatment along with a topical medication can help people with nail fungus get better results than using the laser alone.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05999474 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness and safety of combining fractional CO2 laser treatment with topical tioconazole compared to using Q-switched Nd:YAG laser alone for patients suffering from onychomycosis of the fingernail. The study will involve patients over 18 years of age, assessing various outcomes related to nail health and fungal infection clearance. Participants will be randomly assigned to one of the two treatment groups to determine which method yields better results in treating this condition.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old with any type of onychomycosis.
Not a fit: Patients who are pregnant, have localized bacterial infections around the nail, or have other nail diseases that could interfere with treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a more effective and safer option for patients suffering from onychomycosis.
How similar studies have performed: While the combination of laser treatments with topical antifungals is a relatively novel approach, similar studies have shown promising results in treating fungal infections.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Age group \>18 years. * Patients of both genders. * Patients with OM any type. Exclusion Criteria: * • Pregnancy * Localized bacterial infection around the affected nail * Concomitant nails disease that causes nail dystrophy or discoloration such as psoriasis, lichen planus and atopic dermatitis that may interfere with diagnosis and treatment * Hypersensitivity to terbinafine * Intake of oral antifungal medication within the last 3 months or used topical antifungal medication within the last 2 weeks prior to the laser treatment
Where this trial is running
Cairo
- Kasr Alainy Faculty of Medicine — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Amira Elbendary, MD
- Email: aelbendary@kasralainy.edu.eg
- Phone: 01555668584
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.