Treatment of multiple gingival recessions using advanced surgical techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of a coronally advanced flap (CAF) combined with a deepithelialized free gingival graft (D-FGG) in treating multiple gingival recessions in systemically healthy patients. The study will involve 50 participants who will undergo a split-mouth design, where each side of the jaw will receive a different surgical technique. Randomization will determine the method of de-epithelialization used for the grafts, and clinical parameters will be assessed before and after the procedures to measure outcomes. The trial is structured according to the CONSORT guidelines to ensure rigorous methodology.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 60 years,
* Non-smokers or consumption of up to 10 cigarettes per day,
* no signs of gingival inflammation,
* Presence of at least two single-rooted teeth with type I gingival recession ≥2 mm deep on the buccal side on both sides of the jaw,
* Plaque index (PI) and gingival bleeding on provocation (BOP) \<15% and probing depth (PPD) \<3 mm,
* Absence of non-carious cervical lesions (NCL) and undetectable cemento-enamel junctionr (CEJ) at defect sites,
* No history of previous periodontal plastic surgery on the affected teeth.

Exclusion Criteria:

* Presence of carious lesions or restorations in the CEJ area,
* Use of medications that affect periodontal health and healing,
* Medical contraindications for periodontal surgical procedures,
* Pregnancy and breastfeeding.

Where it's running

• Natasa Nikolic Jakoba
  Belgrade, Serbia Recruiting

Study contacts

• Principal investigator: Natasa Nikolic Jakoba, DDS, PhD — School of Dental Medicine, University of Belgrade, Serbia
• Study coordinator: Natasa Nikolic Jakoba, DDS, PhD
• Email: natasa.nikolic.jakoba@stomf.bg.ac.rs
• Phone: +381638269909

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.