Treatment of multiple gingival recessions using advanced surgical techniques
The Use of Coronary Displaced Flap and Deepithelialized Free Graft in the Treatment of Multiple Adjacent Gingival Recessions - A Randomized Controlled Clinical Study
This study is testing a new surgical method for treating multiple gum recessions to see if it works better than another technique in healthy patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | University of Belgrade Academic / other |
| Locations | 1 site (Belgrade) |
| Trial ID | NCT05664373 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of a coronally advanced flap (CAF) combined with a deepithelialized free gingival graft (D-FGG) in treating multiple gingival recessions in systemically healthy patients. The study will involve 50 participants who will undergo a split-mouth design, where each side of the jaw will receive a different surgical technique. Randomization will determine the method of de-epithelialization used for the grafts, and clinical parameters will be assessed before and after the procedures to measure outcomes. The trial is structured according to the CONSORT guidelines to ensure rigorous methodology.
Who should consider this trial
Good fit: Ideal candidates for this study are non-smoking adults aged 18 to 60 with specific types of gingival recession and no signs of inflammation.
Not a fit: Patients with carious lesions, those on medications affecting periodontal health, or with medical contraindications will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the treatment outcomes for patients with multiple gingival recessions.
How similar studies have performed: Previous studies have shown promising results with similar surgical techniques in periodontal plastic surgery, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 60 years, * Non-smokers or consumption of up to 10 cigarettes per day, * no signs of gingival inflammation, * Presence of at least two single-rooted teeth with type I gingival recession ≥2 mm deep on the buccal side on both sides of the jaw, * Plaque index (PI) and gingival bleeding on provocation (BOP) \<15% and probing depth (PPD) \<3 mm, * Absence of non-carious cervical lesions (NCL) and undetectable cemento-enamel junctionr (CEJ) at defect sites, * No history of previous periodontal plastic surgery on the affected teeth. Exclusion Criteria: * Presence of carious lesions or restorations in the CEJ area, * Use of medications that affect periodontal health and healing, * Medical contraindications for periodontal surgical procedures, * Pregnancy and breastfeeding.
Where this trial is running
Belgrade
- Natasa Nikolic Jakoba — Belgrade, Serbia (Recruiting)
Study contacts
- Principal investigator: Natasa Nikolic Jakoba, DDS, PhD — School of Dental Medicine, University of Belgrade, Serbia
- Study coordinator: Natasa Nikolic Jakoba, DDS, PhD
- Email: natasa.nikolic.jakoba@stomf.bg.ac.rs
- Phone: +381638269909
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.