Treatment of large jaw cysts using endoscopy and navigation technology

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of endoscopic and intraoperative navigation techniques in the removal of giant mandibular bone cysts compared to traditional surgical methods. The primary focus is to reduce the rate of postoperative nerve injury, specifically targeting the inferior alveolar nerve. Patients aged 18 to 75 with odontogenic cystic lesions will undergo imaging examinations to confirm eligibility before receiving the innovative surgical treatment. The study will evaluate nerve function before and one month after surgery, with a secondary focus on recurrence rates one year post-operation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. They are between 18 and 75 years old
2. Imaging and puncture pathology showed odontogenic cystic lesion of the mandible
3. Cystic lesions greater than or equal to 2cm in diameter and spread to the inferior alveolar nerve
4. New or recurrent cyst lesions, or odontogenic cystic lesions that are still greater than or equal to 2cm after other treatment such as fenestration and affecting the lower alveolar nerve
5. No serious systemic disease, tolerant of general anesthesia
6. Patients undergoing surgical treatment for mandibular bone cysts under general anesthesia
7. There was no inferior alveolar nerve injury before operation
8. Have not participated in other clinical trials within 30 days
9. Patients who volunteer to participate in the program and sign informed consent

Exclusion Criteria:

1. The patient has severe systemic disease or pregnancy, and is judged to be unable to tolerate the course of this clinical study and cannot tolerate general anesthesia after evaluation by the research team and multidisciplinary consultation
2. Inability to complete the entire clinical research process due to personal, social, and economic reasons
3. Patients with psychiatric disorders or inability to perceive and communicate normally, such as schizophrenia, claustrophobia, etc., are unable to complete the examination and cooperate in the entire clinical research process

Where it's running

• WangYan
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Principal investigator: Yan Wang — Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
• Study coordinator: Yan Wang
• Email: wangy573@mail.sysu.edu.cn
• Phone: 13825119105

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.