Treatment for wide neck saccular cerebral aneurysms using endovascular techniques
Endovascular Treatment of Wide Neck Saccular Cerebral Aneurysms
This study is testing a new way to treat wide neck brain aneurysms using special coils to see if it can safely reduce the risk of bleeding for patients with these types of aneurysms.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT05796986 on ClinicalTrials.gov |
What this trial studies
This clinical trial focuses on the endovascular treatment of wide neck saccular cerebral aneurysms, which are characterized by a neck diameter greater than 4 mm or a dome-to-neck ratio of less than 2. The procedure involves depositing detachable platinum coils into the aneurysm through a microcatheter to reduce blood flow and promote thrombus formation. The study aims to evaluate the effectiveness and safety of this treatment approach for patients who have experienced spontaneous subarachnoid hemorrhage or have unruptured wide neck aneurysms. Despite advancements in endovascular techniques, treating wide-necked aneurysms remains challenging, and this trial seeks to address those challenges.
Who should consider this trial
Good fit: Ideal candidates include patients with spontaneous subarachnoid hemorrhage due to ruptured wide neck saccular cerebral aneurysms or those with unruptured denovo wide neck saccular cerebral aneurysms.
Not a fit: Patients with other forms of cerebral aneurysms, such as fusiform or dissecting types, or those with complex aneurysms like giant or thrombosed aneurysms, may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce the risk of rupture and improve outcomes for patients with wide neck saccular cerebral aneurysms.
How similar studies have performed: Other studies have shown varying degrees of success with endovascular treatments for cerebral aneurysms, but the specific approach for wide neck saccular aneurysms remains a challenging area with ongoing research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients of spontaneous subarachnoid haemorrhage due to ruptured wide neck saccular cerebral aneurysms * unruptured Denovo wide neck saccular cerebral aneurysms Exclusion Criteria: * other forms of cerebral aneurysms rather than saccular type : fusiform and dissecting aneurysms * complex aneurysms : giant and thrombosed aneyrsms * any spontaneous subarachnoid haemorrhage with world fedriation of neurosurgery societies (WFNS) Grade 4\&5 * Any patient unfit for general anesethia or has serious renal impairment
Where this trial is running
Sohag
- Sohag University Hospital — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohmed A Awesh, assistant lecturer
- Email: mohamed.ayman@med.sohag.edu.eg
- Phone: 01068368550
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.